|
|
| PID | QueryLength | FocusSite | TITLE |
| 27906 | 918 | 517 A | RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor; |
| AC/ID | AC:P40189 ID:IL6RB_HUMAN |
| Feature Table for 517-th site |
VARIANT: /note="A -> P (in HIES4B; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27 and reduced response to OSM, CNTF and LIF)" /id="VAR_086952" DOMAIN: /note="Fibronectin type-III 4" VAR_SEQ: /note="Missing (in isoform 2)" /id="VSP_001685" TOPO_DOM: /note="Extracellular" VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951" CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899" |
| VARIANT for 517-th site |
A->P LP/P " Hyper-IgE syndrome 4B, autosomal recessive, with recurrent infections (HIES4B) " [MIM:618523] |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
|
A:32% S:15% L:13% T:11% G:10% K:6% D:4% R:2% H:2% M:2% P:2% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 8d82 |
(coil) | e (exposed) | 25.9 |
 [Back to SiteTable] |
 [Back to Search Page] |
 [Back to Top Page] |
Summary for the 517-th Site(A)