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| PID | QueryLength | FocusSite | TITLE |
| 27906 | 918 | 499 V | RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor; |
| AC/ID | AC:P40189 ID:IL6RB_HUMAN |
| Feature Table for 499-th site |
VARIANT: /note="V -> I (in dbSNP:rs34417936)" /id="VAR_047786" STRAND: DOMAIN: /note="Fibronectin type-III 4" VAR_SEQ: /note="Missing (in isoform 2)" /id="VSP_001685" TOPO_DOM: /note="Extracellular" VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951" CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899" |
| VARIANT for 499-th site |
V->I LB/B dbSNP:rs3441793 " -" |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
|
V:24% I:14% L:12% Y:11% C:8% R:6% F:6% A:5% M:4% Q:3% E:2% S:2% T:2% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 8d82 |
E (beta-strand) | b (buried) | 4.0 |
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Summary for the 499-th Site(V)