Summary for the 493-rd Site(L)

PID QueryLength FocusSite TITLE
27906 918 493 L RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 493-th site STRAND:
DOMAIN: /note="Fibronectin type-III 4"
VAR_SEQ: /note="Missing (in isoform 2)" /id="VSP_001685"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
E:19% R:12% S:11% N:10% H:8% L:8% I:6% Y:6% Q:5% G:5% A:2% K:2% F:2% T:2% V:2% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 E (beta-strand) e (exposed) 21.3
3D Complex Information
Predicted Bind Molecules
hetero:2 precipitant:1
Templates for 3D complexes
hetero [36127 ] 8av2_A_1_C_1 8av2_B_1_D_1 precipitant [EDO ] 3l5i_A_1_I_1


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