Summary for the 453-rd Site(Y)

PID QueryLength FocusSite TITLE
27906 918 453 Y RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 453-th site STRAND:
VAR_SEQ: /note="Missing (in isoform 3)" /id="VSP_043716"
DOMAIN: /note="Fibronectin type-III 4"
VAR_SEQ: /note="Missing (in isoform 2)" /id="VSP_001685"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
Y:47% G:9% H:7% R:5% L:5% K:5% Q:4% F:4% T:3% W:3% A:2% I:2% V:2% E:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 E (beta-strand) b (buried) 0.9


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