Summary for the 310-th Site(W)
PID QueryLength FocusSite TITLE
27906 918 310 W RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 310-th site MOTIF: /note="WSXWS motif"
DOMAIN: /note="Fibronectin type-III 2"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
W:51% P:9% F:7% S:4% Y:4% D:3% E:3% L:3% A:2% G:2% K:2% T:2% V:2% R:1% N:1% C:1% Q:1% H:1% I:1% M:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 (coil) e (exposed) 30.3
3D Complex Information
Predicted Bind Molecules
hetero:3 homo:1 metal:8 precipitant:4
Templates for 3D complexes
hetero [51447 ] 6p67_G_1_L_1 6p67_I_1_F_1 [49677 ] 8iow_A_1_C_1 homo [48861:IL6RB_HUMAN ] 1bqu_B_1_A_1 metal [IOD ] 1pvh_A_1_E_1 [CL ] 3mzg_B_1_D_1 3n06_B_1_E_1 3n0p_B_1_E_1 3ncb_B_1_F_1 3ncc_B_1_E_1 3nce_B_1_H_1 3ncf_B_1_E_1 precipitant [SO4 ] 1bqu_A_1_E_1 7dc8_C_1_L_1 7dc8_F_1_R_1 [CO3 ] 3d48_B_1_D_1


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