Summary for the 307-th Site(K)

PID QueryLength FocusSite TITLE
27906 918 307 K RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 307-th site STRAND:
DOMAIN: /note="Fibronectin type-III 2"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
K:20% H:8% L:8% R:7% I:7% A:6% Y:6% E:5% N:4% F:4% T:4% D:3% C:3% G:3% P:3% S:3% V:3% Q:2% M:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 S (bend) e (exposed) 52.8
3D Complex Information
Predicted Bind Molecules
hetero:23 homo:1 metal:1
Templates for 3D complexes
hetero [46714:SOMA_HUMAN ] 1bp3_B_1_A_1 [42194:IL6_HUMAN ] 1p9m_C_1_B_1 1p9m_C_2_B_2 5fuc_C_1_B_1 8d82_A_1_B_1 8d82_D_1_E_1 8qy6_C_1_B_1 8qy6_E_1_D_1 [46475:PRL_HUMAN ] 3d48_B_1_A_1 [45993:PRL_HUMAN ] 3mzg_B_1_A_1 3n06_B_1_A_1 3n0p_B_1_A_1 3ncb_B_1_A_1 [42141:IL6_HUMAN ] 5fuc_D_1_A_1 [51447 ] 6p67_I_1_F_1 [57518 ] 7dc8_C_1_B_1 7dc8_F_1_E_1 [15620 ] 7opb_C_1_F_1 [37484:LEP_HUMAN ] 8avf_D_1_C_1 8avf_F_1_E_1 [49527:CLCF1_HUMAN ] 8d7h_A_1_B_1 8d7h_D_1_E_1 8d7r_B_1_A_1 homo [48861:IL6RB_HUMAN ] 1bqu_B_1_A_1 metal [ZN ] 1bp3_B_1_C_1


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