Summary for the 302-nd Site(M)

PID QueryLength FocusSite TITLE
27906 918 302 M RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 302-th site STRAND:
DOMAIN: /note="Fibronectin type-III 2"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
K:16% R:13% Y:9% V:9% A:8% Q:8% I:8% S:7% M:4% T:4% C:3% E:2% G:2% H:2% L:2% F:1% W:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 E (beta-strand) b (buried) 3.4
3D Complex Information
Predicted Bind Molecules
hetero:14 precipitant:1
Templates for 3D complexes
hetero [31663:IL4_HUMAN ] 3bpn_C_1_A_1 [28229:IL13_HUMAN ] 5e4e_C_1_A_1 [51447 ] 6p67_G_1_L_1 6p67_I_1_F_1 [49527:CLCF1_HUMAN ] 8d7h_C_1_B_1 8d7h_F_1_E_1 [42785:IL11_HUMAN ] 8dpt_C_1_B_1 8dpt_F_1_E_1 8dpu_C_1_B_1 8dpu_F_1_E_1 8dpu_I_1_H_1 8dpu_L_1_K_1 8dpu_O_1_N_1 8dpu_R_1_Q_1 precipitant [SO4 ] 6o4p_B_1_P_1


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