Summary for the 3201-st Site(L)
PID QueryLength FocusSite TITLE
31440 4405 3201 L RecName: Full=Replicase polyprotein 1a; Short=pp1a;AltName: Full=ORF1a polyprotein;Contains: RecName: Full=Host translation inhibitor nsp1; AltName: Full=Leader protein; AltName: Full=Non-structural protein 1; Short=nsp1;Contains: RecName: Full=Non-structural protein 2; Short=nsp2; AltName: Full=p65 homolog;Contains: RecName: Full=Papain-like protease nsp3 ; EC=3.4.19.12 ; EC=3.4.22.-; AltName: Full=Non-structural protein 3; Short=nsp3; AltName: Full=PL2-PRO; AltName: Full=Papain-like proteinase; Short=PL-PRO;Contains: RecName: Full=Non-structural protein 4; Short=nsp4;Contains: RecName: Full=3C-like proteinase nsp5; Short=3CL-PRO; Short=3CLp; EC=3.4.22.69; AltName: Full=Main protease; Short=Mpro ; AltName: Full=Non-structural protein 5; Short=nsp5; AltName: Full=SARS coronavirus main proteinase;Contains: RecName: Full=Non-structural protein 6; Short=nsp6;Contains: RecName: Full=Non-structural protein 7; Short=nsp7;Contains: RecName: Full=Non-structural protein 8; Short=nsp8;Contains: RecName: Full=RNA-capping enzyme subunit nsp9; AltName: Full=Non-structural protein 9; Short=nsp9; EC=2.7.7.50 ;Contains: RecName: Full=Non-structural protein 10; Short=nsp10; AltName: Full=Growth factor-like peptide; Short=GFL;Contains: RecName: Full=Non-structural protein 11; Short=nsp11;
UniProt Information
AC/IDAC:P0DTC1 ID:R1A_SARS2
Feature Table for 3201-th site VARIANT: /note="L -> F (in strain: Omicron/BA.2, Omicron/BA.2.12.1, Omicron/BA.2.75, Omicron/XBB.1.5, Omicron/EG.5.1)"
VARIANT: /note="L -> P (in strain: Iota/B.1.526, Lambda/C.37 and Theta/P.3)"
DOMAIN: /note="Nsp4C"
TOPO_DOM: /note="Cytoplasmic"
CHAIN: /note="Non-structural protein 4" /id="PRO_0000449638"
CHAIN: /note="Replicase polyprotein 1a" /id="PRO_0000449634"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
L:20% D:19% P:13% T:12% I:11% S:8% N:6% A:1% R:1% Q:1% E:1% G:1% K:1% F:1% Y:1% V:1%


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