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| PID | QueryLength | FocusSite | TITLE |
| 3025 | 967 | 291 E | RecName: Full=Aminopeptidase N ; Short=AP-N; Short=hAPN; EC=3.4.11.2 ;AltName: Full=Alanyl aminopeptidase;AltName: Full=Aminopeptidase M; Short=AP-M;AltName: Full=Microsomal aminopeptidase;AltName: Full=Myeloid plasma membrane glycoprotein CD13;AltName: Full=gp150;AltName: CD_antigen=CD13; |
| AC/ID | AC:P15144 ID:AMPN_HUMAN |
| Feature Table for 291-th site |
MUTAGEN: /note="E->N: No change of receptor activity and HCoV-229E infection." MUTAGEN: /note="EKQ->NKT: Complete loss of receptor activity and blocks HCoV-229E infection. No loss of enzymatic activity." STRAND: REGION: /note="Necessary and sufficient to mediate interaction with HCoV-229E" ECO:0000269|PubMed:8887485" MUTAGEN: /note="DYVEKQAS->QSVEETAQ: No change in receptor activity and HCoV-229E infection." MUTAGEN: /note="DYVEKQAS->QSVNEQAQ: No change in receptor activity and HCoV-229E infection." MUTAGEN: /note="DYVEKQAS->QSVNETAQ: Complete loss of receptor activity and blocks HCoV-229E infection. No loss of enzymatic activity." REGION: /note="Metalloprotease" TOPO_DOM: /note="Extracellular" CHAIN: /note="Aminopeptidase N" /id="PRO_0000095081" |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
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E:28% S:16% T:9% K:8% A:6% Q:5% L:4% N:3% D:3% P:3% R:2% G:2% H:2% I:2% Y:2% V:2% C:1% M:1% F:1% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 5lhd |
E (beta-strand) | e (exposed) | 52.3 |
| Predicted Bind Molecules |
| hetero:9 compound:3 |
| Templates for 3D complexes |
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hetero [37412:SPIKE_CVH22
] 6atk_A_1_E_1 [37424:SPIKE_CVH22
] 6atk_B_1_D_1 [37496:SPIKE_CVH22
] 6atk_C_1_F_1 [37287 ] 6u7e_A_1_C_1 [37286 ] 6u7e_B_1_D_1 [37285 ] 6u7f_A_1_C_1 [37223 ] 6u7f_B_1_D_1 [37248:H1AG31_CVH22
] 6u7g_A_1_C_1 6u7g_B_1_D_1
compound [NAG ] 4f5c_B_1_V_1 5lds_D_1_MA_1 5lds_D_3_MA_3
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Summary for the 291-st Site(E)