Summary for the 487-th Site(T)

PID QueryLength FocusSite TITLE
14620 1255 487 T RecName: Full=Spike glycoprotein ; Short=S glycoprotein ;AltName: Full=E2 ;AltName: Full=Peplomer protein ;Contains: RecName: Full=Spike protein S1 ;Contains: RecName: Full=Spike protein S2 ;Contains: RecName: Full=Spike protein S2' ;Flags: Precursor;
UniProt Information
AC/IDAC:P59594 ID:SPIKE_SARS
Feature Table for 487-th site VARIANT: /note="T -> S (in strain: Isolate GD03 and Isolate SZ3; 20fold decrease of affinity with human ACE2; decrease of affinity with palm civet ACE2)"
STRAND:
REGION: /note="Receptor-binding motif; binding to human ACE2"
DOMAIN: /note="BetaCoV S1-CTD"
REGION: /note="Receptor-binding domain (RBD)"
CHAIN: /note="Spike protein S1" /id="PRO_0000037209"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Spike glycoprotein" /id="PRO_0000037208"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
T:25% V:23% S:18% I:10% Y:10% N:6% A:1% R:1% D:1% E:1% G:1% L:1% K:1% P:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
6acd S (bend) e (exposed) 27.9
3D Complex Information
Predicted Bind Molecules
hetero:3
Templates for 3D complexes
hetero [94447:ACE2_HUMAN ] 6acg_C_1_D_1 6acj_C_1_D_1 6ack_C_1_D_1


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