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| PID | QueryLength | FocusSite | TITLE |
| 18353 | 805 | 273 R | RecName: Full=Angiotensin-converting enzyme 2; EC=3.4.17.23 ;AltName: Full=Angiotensin-converting enzyme homolog ; Short=ACEH ;AltName: Full=Angiotensin-converting enzyme-related carboxypeptidase ; Short=ACE-related carboxypeptidase; EC=3.4.17.- ;AltName: Full=Metalloprotease MPROT15 ;Contains: RecName: Full=Processed angiotensin-converting enzyme 2 ;Flags: Precursor; |
| AC/ID | AC:Q9BYF1 ID:ACE2_HUMAN |
| Feature Table for 273-th site |
BINDING: /ligand="substrate" MUTAGEN: /note="R->Q: Complete loss of enzyme activity. Does not affect amino acid transport activity of SLC6A19." ECO:0000269|PubMed:19185582" VAR_SEQ: /note="MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNT NITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSED KSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRS EVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHT FEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQK PNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPT AWDLGKGDF -> MREAGWDKGG (in isoform 2)" /id="VSP_060903" DOMAIN: /note="Peptidase M2" CHAIN: /note="Processed angiotensin-converting enzyme 2" /id="PRO_0000292268" TOPO_DOM: /note="Extracellular" CHAIN: /note="Angiotensin-converting enzyme 2" /id="PRO_0000028570" |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
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Q:63% R:23% G:14% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 7v61 |
S (bend) | b (buried) | 14.2 |
| Predicted Bind Molecules |
| compound:1 metal:5 precipitant:4 |
| Templates for 3D complexes |
|
compound [XX5 ] 1r4l_A_1_J_1
metal [ZN ] 7pki_A_1_N_1 7rpv_A_1_O_1 7rpv_C_1_V_1 7rpv_G_1_JA_1 [CL ] 8df5_F_1_JB_1
precipitant [SO4 ] 7dmu_A_1_P_1 7dmu_C_1_T_1 [EDO ] 7p19_A_1_H_1 7p19_C_1_N_1
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Summary for the 273-rd Site(R)