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| PID | QueryLength | FocusSite | TITLE |
| 18353 | 805 | 33 N | RecName: Full=Angiotensin-converting enzyme 2; EC=3.4.17.23 ;AltName: Full=Angiotensin-converting enzyme homolog ; Short=ACEH ;AltName: Full=Angiotensin-converting enzyme-related carboxypeptidase ; Short=ACE-related carboxypeptidase; EC=3.4.17.- ;AltName: Full=Metalloprotease MPROT15 ;Contains: RecName: Full=Processed angiotensin-converting enzyme 2 ;Flags: Precursor; |
| AC/ID | AC:Q9BYF1 ID:ACE2_HUMAN |
| Feature Table for 33-th site |
MUTAGEN: /note="N->D: Increases slightly the interaction with RBD domain of SARS-CoV-2 spike protein." REGION: /note="Interaction with SARS-CoV spike glycoprotein" HELIX: VAR_SEQ: /note="MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNT NITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSED KSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRS EVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHT FEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQK PNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPT AWDLGKGDF -> MREAGWDKGG (in isoform 2)" /id="VSP_060903" DOMAIN: /note="Peptidase M2" CHAIN: /note="Processed angiotensin-converting enzyme 2" /id="PRO_0000292268" TOPO_DOM: /note="Extracellular" CHAIN: /note="Angiotensin-converting enzyme 2" /id="PRO_0000028570" |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
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N:60% E:21% D:19% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 7v61 |
H (alpha-helix) | b (buried) | 20.0 |
| Predicted Bind Molecules |
| hetero:4 metal:1 |
| Templates for 3D complexes |
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hetero [34966:SPIKE_CVHNL
] 3kbh_A_1_B_1 3kbh_C_1_D_1 3kbh_E_1_F_1 3kbh_G_1_H_1
metal [CL ] 7l0n_I_1_QA_1
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Summary for the 33-rd Site(N)