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| PID | QueryLength | FocusSite | TITLE |
| 18353 | 805 | 29 L | RecName: Full=Angiotensin-converting enzyme 2; EC=3.4.17.23 ;AltName: Full=Angiotensin-converting enzyme homolog ; Short=ACEH ;AltName: Full=Angiotensin-converting enzyme-related carboxypeptidase ; Short=ACE-related carboxypeptidase; EC=3.4.17.- ;AltName: Full=Metalloprotease MPROT15 ;Contains: RecName: Full=Processed angiotensin-converting enzyme 2 ;Flags: Precursor; |
| AC/ID | AC:Q9BYF1 ID:ACE2_HUMAN |
| Feature Table for 29-th site |
MUTAGEN: /note="L->F: Increases slightly the interaction with RBD domain of SARS-CoV-2 spike protein." HELIX: VAR_SEQ: /note="MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNT NITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSED KSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRS EVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHT FEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQK PNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPT AWDLGKGDF -> MREAGWDKGG (in isoform 2)" /id="VSP_060903" DOMAIN: /note="Peptidase M2" CHAIN: /note="Processed angiotensin-converting enzyme 2" /id="PRO_0000292268" TOPO_DOM: /note="Extracellular" CHAIN: /note="Angiotensin-converting enzyme 2" /id="PRO_0000028570" |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
|
L:62% V:19% A:11% F:8% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 7v61 |
H (alpha-helix) | b (buried) | 2.8 |
| Predicted Bind Molecules |
| hetero:2 metal:1 |
| Templates for 3D complexes |
|
hetero [100794:SPIKE_SARS2
] 7wk5_A_1_B_1 7wvp_A_1_B_1
metal [CL ] 7l0n_I_1_QA_1
|
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Summary for the 29-th Site(L)