Summary for the 487-th Site(A)

PID QueryLength FocusSite TITLE
7656 918 487 A RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 487-th site DOMAIN: /note="Fibronectin type-III 4"
VAR_SEQ: /note="Missing (in isoform 2)" /id="VSP_001685"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
K:25% E:12% S:11% T:11% Q:7% V:5% A:4% I:4% F:4% R:3% H:3% Y:3% N:2% D:2% L:2% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 (coil) e (exposed) 41.1
3D Complex Information
Predicted Bind Molecules
homo:4
Templates for 3D complexes
homo [93146:LEPR_MOUSE ] 8avb_B_1_C_1 [99335:LEPR_HUMAN ] 8ave_D_1_B_1 8avf_D_1_B_1 8avo_B_1_F_1


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