Summary for the 284-th Site(F)
PID QueryLength FocusSite TITLE
7656 918 284 F RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 284-th site STRAND:
DOMAIN: /note="Fibronectin type-III 2"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
Y:21% F:18% A:14% V:12% L:9% H:7% C:6% I:4% Q:2% T:2% R:1% N:1% D:1% E:1% G:1% K:1% P:1% S:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 E (beta-strand) b (buried) 13.4
3D Complex Information
Predicted Bind Molecules
hetero:21 homo:6 precipitant:1
Templates for 3D complexes
hetero [48886:IL6RA_HUMAN ] 1p9m_A_1_C_1 1p9m_A_2_C_2 8qy5_A_1_C_1 8qy5_F_1_E_1 8qy6_A_1_C_1 [49093:IL4RA_HUMAN ] 3bpn_C_1_B_1 [49220:IL4RA_HUMAN ] 5e4e_C_1_B_1 [72853:CNTFR_HUMAN ] 8d74_A_1_C_1 8d7r_D_1_B_1 [69686:I11RA_HUMAN ] 8dps_A_1_C_1 8dps_D_1_F_1 8qy4_B_1_E_1 8qy4_D_1_F_1 [69685:I11RA_HUMAN ] 8dpt_A_1_C_1 8dpt_D_1_F_1 8dpu_A_1_C_1 8dpu_D_1_F_1 8dpu_G_1_I_1 8dpu_J_1_L_1 8dpu_M_1_O_1 8dpu_P_1_R_1 homo [50668:PRLR_RAT ] 1f6f_B_1_C_1 [50667:PRLR_RAT ] 1f6f_C_1_B_1 3ew3_C_1_B_1 3npz_B_1_C_1 3npz_C_1_B_1 [54608:PRLR_RAT ] 3ew3_B_1_C_1 precipitant [SO4 ] 1bqu_B_1_J_1


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