Summary for the 281-st Site(R)
PID QueryLength FocusSite TITLE
7656 918 281 R RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 281-th site DOMAIN: /note="Fibronectin type-III 2"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
Q:16% T:15% K:13% R:12% S:8% E:6% L:6% A:5% N:4% G:4% M:3% D:2% H:2% Y:2% I:1% P:1% V:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 (coil) e (exposed) 34.8
3D Complex Information
Predicted Bind Molecules
hetero:26 homo:3 compound:1 precipitant:6
Templates for 3D complexes
hetero [41484:CSF3_HUMAN ] 1cd9_D_1_A_1 [48886:IL6RA_HUMAN ] 1p9m_A_1_C_1 1p9m_A_2_C_2 8qy5_A_1_C_1 8qy5_F_1_E_1 8qy6_A_1_C_1 8qy6_F_1_E_1 [33947 ] 5fuc_C_1_E_1 [33891 ] 5fuc_D_1_F_1 [57598:CRLF2_HUMAN ] 5j11_B_1_C_1 [72853:CNTFR_HUMAN ] 8d74_A_1_C_1 8d7r_D_1_B_1 [73481:IL6RA_HUMAN ] 8d82_C_1_A_1 8d82_F_1_D_1 [69686:I11RA_HUMAN ] 8dps_A_1_C_1 8dps_D_1_F_1 8qy4_B_1_E_1 8qy4_D_1_F_1 [69685:I11RA_HUMAN ] 8dpt_A_1_C_1 8dpt_D_1_F_1 8dpu_A_1_C_1 8dpu_D_1_F_1 8dpu_G_1_I_1 8dpu_J_1_L_1 8dpu_M_1_O_1 8dpu_P_1_R_1 homo [50667:PRLR_RAT ] 1f6f_C_1_B_1 3ew3_C_1_B_1 3npz_C_1_B_1 compound [NAG ] 5mzv_C_1_O_1 precipitant [SO4 ] 1bqu_B_1_J_1 1n26_A_1_F_1 1n26_A_2_F_2 7dc8_C_1_K_1 7dc8_F_1_Q_1 [GOL ] 3up1_A_1_H_1


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