Summary for the 252-nd Site(V)
PID QueryLength FocusSite TITLE
7656 918 252 V RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 252-th site MUTAGEN: /note="V->G: Induces ligand-independent activation."
DOMAIN: /note="Fibronectin type-III 2"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
G:21% S:18% V:17% H:6% E:5% I:5% K:5% R:4% Y:4% D:3% T:3% N:2% Q:2% L:2% F:2%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 T (Hbond turn) e (exposed) 34.7
3D Complex Information
Predicted Bind Molecules
hetero:55 homo:2 compound:1
Templates for 3D complexes
hetero [46714:SOMA_HUMAN ] 1bp3_B_1_A_1 [48411:CSH_SHEEP ] 1f6f_B_1_A_1 [45023:Q98823_HHV8 ] 1i1r_A_1_B_1 1i1r_A_2_B_2 [42194:IL6_HUMAN ] 1p9m_A_1_B_1 1p9m_A_2_B_2 1p9m_C_1_B_1 1p9m_C_2_B_2 5fuc_C_1_B_1 8d82_A_1_B_1 8d82_C_1_B_1 8d82_D_1_E_1 8d82_F_1_E_1 8qy5_A_1_B_1 8qy5_C_1_B_1 8qy5_E_1_D_1 8qy5_F_1_D_1 8qy6_A_1_B_1 8qy6_C_1_B_1 8qy6_E_1_D_1 8qy6_F_1_D_1 [40397:LIF_HUMAN ] 1pvh_C_1_D_1 [41484:CSF3_HUMAN ] 2d9q_B_1_A_1 2d9q_B_2_A_2 [45993:PRL_HUMAN ] 3mzg_B_1_A_1 3n06_B_1_A_1 3n0p_B_1_A_1 3ncb_B_1_A_1 3ncc_B_1_A_1 3nce_B_1_A_1 3ncf_B_1_A_1 3npz_B_1_A_1 [42141:IL6_HUMAN ] 5fuc_D_1_A_1 [33891 ] 5fuc_D_1_F_1 [52964 ] 7dc8_C_1_A_1 7dc8_F_1_D_1 [43070:LEP_HUMAN ] 7z3q_D_1_A_1 [52193:CNTF_HUMAN ] 8d74_A_1_B_1 8d74_C_1_B_1 [49527:CLCF1_HUMAN ] 8d7h_A_1_B_1 8d7h_C_1_B_1 8d7h_D_1_E_1 8d7h_F_1_E_1 8d7r_B_1_A_1 [42785:IL11_HUMAN ] 8dpt_A_1_B_1 8dpt_C_1_B_1 8dpt_D_1_E_1 8dpt_F_1_E_1 8dpu_C_1_B_1 8dpu_F_1_E_1 8dpu_I_1_H_1 8dpu_L_1_K_1 8dpu_O_1_N_1 8dpu_R_1_Q_1 [55385 ] 8iow_A_1_D_1 homo [48861:IL6RB_HUMAN ] 1bqu_A_1_B_1 [47921:IL7RA_HUMAN ] 3up1_B_1_A_1 compound [NAG ] 8iow_A_1_F_1


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