Summary for the 172-nd Site(C)

PID QueryLength FocusSite TITLE
7656 918 172 C RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 172-th site MUTAGEN: /note="C->S: Induces ligand-independent activation."
DISULFID: ECO:0000269|PubMed:20489211"
DOMAIN: /note="Fibronectin type-III 1"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
C:44% S:11% T:8% Y:8% L:6% V:5% A:4% G:3% N:2% Q:2% E:2% I:2% F:2% H:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 E (beta-strand) b (buried) 5.3
3D Complex Information
Predicted Bind Molecules
hetero:1 metal:7 precipitant:2
Templates for 3D complexes
hetero [57909:IL12A_MOUSE ] 8odz_D_1_A_1 metal [NA ] 3mzg_B_1_E_1 3n06_B_1_F_1 3n0p_B_1_F_1 3ncb_B_1_G_1 3ncc_B_1_F_1 3nce_B_1_I_1 3ncf_B_1_F_1 precipitant [EDO ] 3v6o_A_1_M_1 3v6o_A_1_N_1


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