Summary for the 350-th Site(V)

PID QueryLength FocusSite TITLE
27558 918 350 V RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 350-th site STRAND:
DOMAIN: /note="Fibronectin type-III 3"
VAR_SEQ: /note="Missing (in isoform 2)" /id="VSP_001685"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
T:19% F:12% S:12% L:11% V:8% A:7% Q:7% Y:7% H:4% K:4% W:3% R:2% N:2% C:2% I:2% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 E (beta-strand) b (buried) 13.3
3D Complex Information
Predicted Bind Molecules
hetero:1 precipitant:1
Templates for 3D complexes
hetero [93729:I12R1_MOUSE :DAPK1_HUMAN ] 8oe0_D_1_C_1 precipitant [EDO ] 3l5i_A_1_J_1


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