Summary for the 294-th Site(E)

PID QueryLength FocusSite TITLE
27558 918 294 E RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 294-th site STRAND:
DOMAIN: /note="Fibronectin type-III 2"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
E:24% K:15% V:11% T:9% S:6% A:5% R:5% N:5% L:4% M:3% P:3% D:2% G:2% I:2% Y:2% C:1% Q:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 E (beta-strand) e (exposed) 30.7
3D Complex Information
Predicted Bind Molecules
hetero:2 homo:3
Templates for 3D complexes
hetero [55912 ] 6p67_J_1_C_1 6p67_K_1_A_1 homo [73481:IL6A_HUMAN ] 1n26_A_2_A_1 [82010:CRLF1_HUMAN ] 8d7h_C_1_F_1 8d7h_F_1_C_1


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