Summary for the 288-th Site(D)
PID QueryLength FocusSite TITLE
27558 918 288 D RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 288-th site DOMAIN: /note="Fibronectin type-III 2"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
D:37% G:25% N:12% K:10% S:6% E:5% Y:2%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 S (bend) e (exposed) 95.1
3D Complex Information
Predicted Bind Molecules
hetero:23 homo:8 precipitant:3
Templates for 3D complexes
hetero [69804:IL6RB_HUMAN ] 1p9m_C_1_A_1 1p9m_C_2_A_2 8dpu_C_1_A_1 8dpu_F_1_D_1 8dpu_I_1_G_1 8dpu_L_1_J_1 8dpu_O_1_M_1 8dpu_R_1_P_1 [49093:IL4RA_HUMAN ] 3bpn_C_1_B_1 [83825:NET1_HUMAN ] 4urt_B_2_A_2 [49220:IL4RA_HUMAN ] 5e4e_C_1_B_1 [57598:CRLF2_HUMAN ] 5j11_B_1_C_1 [72853:CNTFR_HUMAN ] 8d74_A_1_C_1 [95320:IL6RB_HUMAN ] 8d74_C_1_A_1 8d7r_B_1_D_1 [94283:IL6RB_HUMAN ] 8d82_A_1_C_1 8d82_D_1_F_1 [94347:IL6RB_HUMAN ] 8dpt_C_1_A_1 8dpt_F_1_D_1 [99810:IL6RB_MOUSE ] 8qy5_C_1_A_1 8qy5_E_1_F_1 8qy6_C_1_A_1 8qy6_E_1_F_1 homo [50668:PRLR_RAT ] 1f6f_B_1_C_1 [50667:PRLR_RAT ] 1f6f_C_1_B_1 3ew3_C_1_B_1 3npz_B_1_C_1 3npz_C_1_B_1 [54608:PRLR_RAT ] 3ew3_B_1_C_1 [69572:A0A161FW14_MESMA ] 7y8s_A_1_B_1 7y8s_B_1_A_1 precipitant [EDO ] 3v6o_A_1_K_1 7opb_A_1_H_1 [SO4 ] 4urt_B_2_O_2


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