Summary for the 818-th Site(N) |
PID | QueryLength | FocusSite | TITLE |
845549 | 918 | 818 N | RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor; |
AC/ID | AC:P40189 ID:IL6RB_HUMAN |
Feature Table for 818-th site |
MUTAGEN: /note="Missing: Results in impaired cytokine-mediated signaling pathway with loss of response to IL-6 and IL-11. Weak response to IL-27, OSM and LIF." VARIANT: /note="Missing (in HIES4A; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, OSM, LIF and a weak response to IL-27)" /id="VAR_086955" VARIANT: /note="Missing (in HIES4A; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, OSM and LIF and a weak response to IL-27)" /id="VAR_086954" VARIANT: /note="Missing (in HIES4A; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, OSM and LIF and a weak response to IL-27)" /id="VAR_086953" TOPO_DOM: /note="Cytoplasmic" VAR_SEQ: /note="Missing (in isoform 2)" /id="VSP_001685" VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951" CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899" |
Percentages of Amino Acids in Homologous Proteins [show alignment] |
N:68% S:32% |
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