Summary for the 190-th Site(Y) |
PID | QueryLength | FocusSite | TITLE |
7656 | 918 | 190 Y | RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor; |
AC/ID | AC:P40189 ID:IL6RB_HUMAN |
Feature Table for 190-th site |
MUTAGEN: /note="Y->G: Does not induce ligand-independent activation." STRAND: VARIANT: /note="Missing (in IMD94; results in constitutively active IL6-mediated signaling and constitutive phosphorylation of STAT3 in patient cells)" /id="VAR_086950" MUTAGEN: /note="Missing: Induces ligand-independent activation." DOMAIN: /note="Fibronectin type-III 1" TOPO_DOM: /note="Extracellular" CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899" |
Percentages of Amino Acids in Homologous Proteins [show alignment] |
Y:23% L:16% F:14% S:8% K:7% M:6% W:5% R:4% H:4% V:4% G:3% I:2% T:2% |
Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
8d82 | (coil) | e (exposed) | 22.6 |
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