Summary for the 279-th Site(R)
PID QueryLength FocusSite TITLE
30181 425 279 R RecName: Full=Mothers against decapentaplegic homolog 3; Short=MAD homolog 3; Short=Mad3; Short=Mothers against DPP homolog 3; Short=hMAD-3;AltName: Full=JV15-2;AltName: Full=SMAD family member 3; Short=SMAD 3; Short=Smad3; Short=hSMAD3;
UniProt Information
AC/IDAC:P84022 ID:SMAD3_HUMAN
Feature Table for 279-th site VARIANT: /note="R -> K (in LDS3; dbSNP:rs387906852)" /id="VAR_067048"
REGION: /note="Sufficient for interaction with XPO4"
DOMAIN: /note="MH2"
CHAIN: /note="Mothers against decapentaplegic homolog 3" /id="PRO_0000090856"
VARIANT for 279-th site R->K LP/P dbSNP:rs3879068 " Loeys-Dietz syndrome 3 (LDS3) " [MIM:613795]
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
R:92% K:8%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1mk2 (coil) e (exposed) 24.1
3D Complex Information
Predicted Bind Molecules
hetero:1
Templates for 3D complexes
hetero [58584:SMAD4_HUMAN ] 1u7f_C_1_B_1


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