Summary for the 354-th Site(E)
PID QueryLength FocusSite TITLE
29066 529 354 E RecName: Full=Importin subunit alpha-1 ;AltName: Full=Karyopherin subunit alpha-2;AltName: Full=RAG cohort protein 1;AltName: Full=SRP1-alpha;
UniProt Information
AC/IDAC:P52292 ID:IMA1_HUMAN
Feature Table for 354-th site HELIX:
REPEAT: /note="ARM 7"
REGION: /note="NLS binding site (minor)"
CHAIN: /note="Importin subunit alpha-1" /id="PRO_0000120722"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
E:54% Q:14% N:8% H:5% K:4% S:4% Y:4% A:3% C:2% L:2%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5h43 H (alpha-helix) b (buried) 13.6
3D Complex Information
Predicted Bind Molecules
hetero:118 homo:13 compound:4 metal:3 precipitant:10
Templates for 3D complexes
hetero [8232:NUPL_XENLA ] 1ee5_A_1_B_1 [1099:TALA_SV40 ] 1ejl_C_1_A_1 [10381:TALA_SV40 ] 1q1t_C_1_A_1 [15270:NUP2_YEAST ] 1un0_A_1_C_1 1un0_B_1_D_1 [14491:NUP50_MOUSE ] 2c1m_A_1_B_1 [29039 ] 2ru4_B_1_A_1 [4028 ] 2ynr_A_1_C_1 [4030 ] 2yns_A_1_C_1 2yns_B_1_D_1 [97802:NCBP1_HUMAN ] 3fex_C_1_A_1 3fey_C_1_A_1 [20520:Q9I8N0_XENLA ] 3knd_A_1_B_1 [5613 ] 3l3q_A_1_C_1 [4375:PLS4_HUMAN ] 3q5u_A_1_B_1 [11155 ] 3ukw_A_1_B_1 [11186 ] 3ukx_A_1_B_1 [10194:NCBP1_MOUSE ] 3ukz_A_1_B_1 3ul0_A_1_B_1 [8873:NUPL_XENLA ] 3ul1_A_1_B_1 4bpl_A_1_B_1 [4892:DDX21_MOUSE ] 3zin_A_1_B_1 [3957 ] 3zio_A_1_B_1 [3953 ] 3zip_A_1_B_1 [3954 ] 3ziq_A_1_C_1 [3335 ] 3zir_A_1_B_1 [8369:TERT_HUMAN ] 4b18_A_1_B_1 [8396:VIRD2_AGRT5 ] 4bqk_A_1_D_1 [8660:VIRD2_AGRT5 ] 4bqk_B_1_C_1 [2694 ] 4d49_B_1_D_1 4d49_E_1_G_1 4d49_F_1_H_1 [4251:DUT_HUMAN ] 4mz5_C_1_A_1 [4483:DUT_HUMAN ] 4mz6_C_1_A_1 [14067:HEH2_YEAST ] 4pvz_A_1_C_1 [13995:HEH2_YEAST ] 4pvz_B_1_D_1 [19715:PB2_I75A3 ] 4uad_A_1_B_1 4uae_A_1_B_1 4uaf_A_1_B_1 [11502:PO121_RAT ] 4yi0_A_1_B_1 [6279:NCAP_I34A1 ] 4zdu_A_1_B_1 [2718 ] 5aei_A_1_D_1 5aei_B_1_E_1 5aei_C_1_F_1 5mfj_A_1_D_1 6sa8_A_1_B_1 [4166:VPR_HV1B9 ] 5b56_A_1_C_1 5b56_B_1_D_1 [15742:SART3_HUMAN ] 5ctt_A_1_B_1 [9861:ERCC5_HUMAN ] 5ekf_C_1_A_1 [12761:B6VDJ7_9FLAV ] 5fc8_B_1_A_1 [47351:ULP1_YEAST ] 5h2w_A_1_B_1 [9733:ULP1_YEAST ] 5h2w_C_1_D_1 5h2x_A_1_B_1 [2500:KAT8_HUMAN ] 5h43_A_1_B_1 [12789:POLG_DEN2P ] 5hhg_B_1_A_1 [6160 ] 5huy_A_1_B_1 [3160 ] 5k9s_A_1_C_1 [23573:DECO_LAMBD ] 5mfd_A_1_B_1 5mfd_C_1_D_1 5mfd_E_1_F_1 5mfd_G_1_H_1 [2861 ] 5mff_A_1_E_1 5mff_B_1_E_1 5mff_C_1_F_1 5mff_D_1_F_1 [1336 ] 5mfk_B_1_D_1 [83247:RCC1_HUMAN ] 5tbk_E_1_K_1 [2443:MLH1_HUMAN ] 5u5p_C_1_A_1 [4658 ] 5umz_A_1_B_1 [4626 ] 5vqi_A_1_C_1 [11258:DPOLM_HUMAN ] 5w4f_A_1_C_1 [4533:EBNA1_EBVB9 ] 5wum_A_1_B_1 [1931:EBNA1_EBVB9 ] 5wun_A_1_B_1 [13695:W_NIPAV ] 6bvv_A_1_B_1 [13697:W_HENDH ] 6bw9_A_1_B_1 6bwa_A_1_B_1 6bwb_A_1_B_1 [9310:TP53B_HUMAN ] 6iu7_A_1_B_1 8hkw_A_1_C_1 8hkw_B_1_D_1 [15478:GOGA2_HUMAN ] 6iw8_B_1_A_1 [12019:GOGA2_HUMAN ] 6iwa_B_1_A_1 [15462:GOGA2_HUMAN ] 6k06_B_1_A_1 [4267:NIT2_NEUCR ] 6p6a_A_1_B_1 [3979 ] 6s9l_A_1_C_1 [3366:MLH1_HUMAN ] 6wba_A_1_B_1 [3364:MLH1_HUMAN ] 6wbb_A_1_B_1 [20463:SOX2_HUMAN ] 6wx8_A_1_B_1 6wx8_C_1_D_1 [9703:HNRPK_HUMAN ] 7cru_B_1_A_1 7cru_D_1_C_1 [9370:TF65_HUMAN ] 7let_A_1_C_1 7leu_A_1_C_1 [9367:TF65_HUMAN ] 7lf4_A_1_F_1 [3306:MLH1_HUMAN ] 7m60_C_1_A_1 [11143 ] 7n8j_A_1_B_1 [9935:TADBP_HUMAN ] 7n9h_A_1_B_1 [8964:T2BB21_MERS ] 7rfx_A_1_B_1 7rfz_A_1_B_1 [8935:T2BB21_MERS ] 7rfy_A_1_B_1 [8315:ORF4B_BCHK5 ] 7rg6_A_1_C_1 [9263:M1LJY4_9FLAV ] 8ech_B_1_A_1 [3378:NS1_PAVHV ] 8f2q_A_1_B_1 [10869 ] 8fzm_A_1_B_1 8fzm_C_1_D_1 [411 ] 8g8q_A_1_C_1 [12315:RELB_HUMAN ] 8g8r_A_1_B_1 [12501:F1S861_PIG ] 8g8s_A_1_B_1 [11685 ] 8gai_A_1_B_1 [11684 ] 8gai_C_1_D_1 [13985:HIF1A_HUMAN ] 8he0_A_1_B_1 [16251:A0A2Z4K4X6_9VIRU ] 8sg7_A_1_B_1 [1542 ] 8sv0_A_1_B_1 [8805:L7REU2_9POLY ] 8tuq_A_1_B_1 [12503:M4VRX3_9POLY ] 8tur_A_1_B_1 [9545:R4L0R1_9POLY ] 8tuu_A_1_B_1 [3049 ] 8tuv_A_1_B_1 homo [49314 ] 4dba_A_1_B_1 4dba_B_1_A_1 4dba_C_1_D_1 4dba_D_1_C_1 [59975 ] 4pls_A_1_B_1 4pls_D_1_C_1 5mfg_A_1_C_1 5mfg_B_1_D_1 5mfg_C_1_A_1 5mfg_D_1_B_1 [87013:Q6FNI4_CANGA :Q6FX18_CANGA ] 7vpt_A_1_A_3 7vpt_A_2_A_1 7vpt_A_3_A_2 compound [ARG ] 4d49_E_1_J_1 [3D4 ] 4u5n_A_1_B_1 [3D2 ] 4u5u_A_1_C_1 [RH2 ] 4u5v_A_1_C_1 metal [MG ] 4db8_B_1_G_1 [CA ] 5mfd_A_1_R_1 5mfd_K_1_DB_1 precipitant [PEG ] 3wpt_A_1_M_1 3wpt_B_1_N_1 [GOL ] 4e4v_B_1_N_1 4v3q_A_1_E_1 4v3q_B_1_N_1 [EDO ] 4wv6_A_1_N_1 [MPD ] 5mfl_A_1_I_1 6s9l_B_1_J_1 [ACT ] 7cru_D_1_I_1 [DTT ] 8g8r_A_1_C_1


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