Summary for the 238-th Site(R)
PID QueryLength FocusSite TITLE
29066 529 238 R RecName: Full=Importin subunit alpha-1 ;AltName: Full=Karyopherin subunit alpha-2;AltName: Full=RAG cohort protein 1;AltName: Full=SRP1-alpha;
UniProt Information
AC/IDAC:P52292 ID:IMA1_HUMAN
Feature Table for 238-th site REPEAT: /note="ARM 4"
REGION: /note="NLS binding site (major)"
CHAIN: /note="Importin subunit alpha-1" /id="PRO_0000120722"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
R:38% K:12% E:11% S:9% H:7% L:4% Y:4% V:4% A:2% N:1% D:1% Q:1% G:1% I:1% F:1% P:1% T:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5h43 (coil) e (exposed) 46.2
3D Complex Information
Predicted Bind Molecules
hetero:198 homo:5 compound:2 metal:3 precipitant:13
Templates for 3D complexes
hetero [2245:MYC_HUMAN ] 1ee4_A_1_B_1 1ee4_D_1_E_1 [8232:NUPL_XENLA ] 1ee5_A_1_B_1 [1099:TALA_SV40 ] 1ejl_C_1_B_1 [6488:NUPL_XENLA ] 1ejy_B_1_A_1 [3261:IMA2_MOUSE ] 1iq1_C_1_B_1 [8650:RB_HUMAN ] 1pjm_B_1_A_1 [9127:IMA2_MOUSE ] 1pjn_B_1_A_1 [11144:TALA_SV40 ] 1q1s_C_1_B_1 [10247:TALA_SV40 ] 1q1t_C_1_B_1 [15270:NUP2_YEAST ] 1un0_A_1_C_1 1un0_B_1_D_1 [2402:PLS1_HUMAN ] 1y2a_A_1_B_1 [14491:NUP50_MOUSE ] 2c1m_A_1_B_1 [15232:NUP2_YEAST ] 2c1t_A_1_C_1 [15233:NUP2_YEAST ] 2c1t_B_1_D_1 [20925:PB2_IAVI7 ] 2jdq_A_1_D_1 2jdq_B_1_C_1 [4029 ] 2ynr_A_1_B_1 [5568:ANDR_HUMAN ] 3btr_A_1_B_1 [97802:NCBP1_HUMAN ] 3fex_C_1_A_1 3fey_C_1_A_1 [20520:Q9I8N0_XENLA ] 3knd_A_1_B_1 [5804 ] 3l3q_A_1_B_1 [2637:CLIC4_HUMAN ] 3oqs_B_1_A_1 [4248:XRCC5_HUMAN ] 3rz9_A_1_B_1 [9210:XRCC6_HUMAN ] 3rzx_A_1_B_1 [28552:NUP50_HUMAN ] 3tj3_A_1_B_1 3tj3_C_1_D_1 [30372 ] 3tpm_A_1_B_1 [11155 ] 3ukw_A_1_B_1 [11186 ] 3ukx_A_1_B_1 [10194:NCBP1_MOUSE ] 3ukz_A_1_B_1 3ul0_A_1_B_1 [8873:NUPL_XENLA ] 3ul1_A_1_B_1 4bpl_A_1_B_1 [8027:FEN1_HUMAN ] 3uvu_B_1_A_1 [3882:Q9WCF8_9VIRU ] 3ve6_A_1_B_1 [5127:DDX21_MOUSE ] 3zin_A_1_C_1 [3956 ] 3zio_A_1_C_1 [3817 ] 3zip_A_1_C_1 [3955 ] 3ziq_A_1_B_1 [3213 ] 3zir_A_1_C_1 [8369:TERT_HUMAN ] 4b18_A_1_B_1 [3045 ] 4b8o_A_1_B_1 [3697 ] 4ba3_A_1_B_1 [8396:VIRD2_AGRT5 ] 4bqk_A_1_D_1 [8660:VIRD2_AGRT5 ] 4bqk_B_1_C_1 [11240:Q68SX0_BFDV ] 4htv_A_1_B_1 [4482:DUT_HUMAN ] 4mz5_C_1_B_1 [4501:DUT_HUMAN ] 4mz6_C_1_B_1 [10818:RCC1_YEAST ] 4oih_A_1_B_1 [14067:HEH2_YEAST ] 4pvz_A_1_C_1 [13995:HEH2_YEAST ] 4pvz_B_1_D_1 [1176:LT_SV40 ] 4rxh_A_1_C_1 [19715:PB2_I75A3 ] 4uad_A_1_B_1 4uae_A_1_B_1 4uaf_A_1_B_1 [4886:TAF8_HUMAN ] 4wv6_A_1_B_1 [15554:SRC1_YEAST ] 4xzr_B_1_A_1 [11502:PO121_RAT ] 4yi0_A_1_B_1 [2718 ] 5aei_A_1_D_1 5aei_B_1_E_1 5aei_C_1_F_1 6sa8_A_1_B_1 [4166:VPR_HV1B9 ] 5b56_A_1_E_1 5b56_B_1_F_1 [15742:SART3_HUMAN ] 5ctt_A_1_B_1 [24235:PARP2_HUMAN ] 5d5k_A_1_B_1 [12737:XRCC1_HUMAN ] 5e6q_A_1_B_1 [9983:ERCC5_HUMAN ] 5ekf_C_1_B_1 [7980 ] 5ekg_C_1_B_1 [12761:B6VDJ7_9FLAV ] 5fc8_B_1_A_1 [10956:NUMA1_HUMAN ] 5gxw_A_1_B_1 [47351:ULP1_YEAST ] 5h2w_A_1_B_1 [9733:ULP1_YEAST ] 5h2w_C_1_D_1 5h2x_A_1_B_1 [5899:KAT8_HUMAN ] 5h43_A_1_C_1 [12789:POLG_DEN2P ] 5hhg_B_1_A_1 [3763 ] 5huw_A_1_B_1 [6440 ] 5huy_A_1_C_1 [3160 ] 5k9s_A_1_B_1 [6441 ] 5klr_A_1_B_1 [6261 ] 5klt_A_1_B_1 [48614:A0A059PIQ0_AEQVI ] 5mfc_A_1_B_1 5mfc_C_1_D_1 [23573:DECO_LAMBD ] 5mfd_A_1_B_1 5mfd_C_1_D_1 5mfd_G_1_H_1 [1423 ] 5mfe_A_1_E_1 [2855 ] 5mfh_A_1_E_1 5mfh_C_1_F_1 [5584 ] 5svz_A_1_B_1 [88967:RCC1_YEAST ] 5t94_B_1_A_1 [83247:RCC1_HUMAN ] 5tbk_A_1_J_1 5tbk_B_1_I_1 5tbk_C_1_P_1 5tbk_D_1_O_1 5tbk_E_1_K_1 5tbk_F_1_L_1 5tbk_G_1_M_1 5tbk_H_1_N_1 [2625:MLH1_HUMAN ] 5u5p_C_1_B_1 [3238:PMS2_HUMAN ] 5u5r_A_1_B_1 [4300 ] 5umz_A_1_C_1 [8181 ] 5v5o_A_1_B_1 [8183:Q45VS8_9INFA ] 5v5p_A_1_B_1 [4377 ] 5vqi_A_1_B_1 [6427 ] 5w4e_A_1_B_1 [11372:DPOLM_HUMAN ] 5w4f_A_1_B_1 [11371:DPOLL_HUMAN ] 5w4g_A_1_B_1 [4534:EBNA1_EBVB9 ] 5wum_A_1_C_1 [1595:EBNA1_EBVB9 ] 5wun_A_1_C_1 [9317:EBNA5_EBVB9 ] 5x8n_A_1_B_1 [11486:RANB3_HUMAN ] 5xzx_A_1_B_1 [13695:W_NIPAV ] 6bvv_A_1_B_1 [13698:W_NIPAV ] 6bw0_B_1_A_1 6bw1_B_1_A_1 [13697:W_HENDH ] 6bw9_A_1_B_1 6bwa_A_1_B_1 6bwb_A_1_B_1 [9310:TP53B_HUMAN ] 6iu7_A_1_B_1 6iua_A_1_B_1 8hkw_A_1_D_1 8hkw_B_1_C_1 [15478:GOGA2_HUMAN ] 6iw8_B_1_A_1 [12019:GOGA2_HUMAN ] 6iwa_B_1_A_1 [15462:GOGA2_HUMAN ] 6k06_B_1_A_1 [2255 ] 6mjl_A_1_B_1 [4626:NIT2_NEUCR ] 6p6a_A_1_C_1 [10036:A0A0B0E960_NEUCS ] 6p6e_A_1_B_1 [3979 ] 6s9l_A_1_C_1 6s9l_B_1_D_1 [3365:MLH1_HUMAN ] 6wba_A_1_C_1 [3096:MLH1_HUMAN ] 6wbb_A_1_C_1 [3211:MLH1_HUMAN ] 6wbc_A_1_B_1 [22407:SOX2_HUMAN ] 6wx7_A_1_B_1 [20463:SOX2_HUMAN ] 6wx8_A_1_B_1 6wx8_C_1_D_1 [22387:SOX2_HUMAN ] 6wx9_A_1_B_1 [9703:HNRPK_HUMAN ] 7cru_B_1_A_1 7cru_D_1_C_1 [10668:KDM1A_HUMAN ] 7jjl_A_1_B_1 7jjm_B_1_A_1 [10526:KDM1A_HUMAN ] 7jk7_B_1_A_1 [4935 ] 7jvo_A_1_B_1 [2567:C0LA97_9VIRU ] 7l04_B_1_A_1 [5125:NFKB1_HUMAN ] 7leq_A_1_B_1 [5027:NFKB1_HUMAN ] 7let_A_1_B_1 [5119:NFKB1_HUMAN ] 7lf4_A_1_B_1 7lf4_C_1_E_1 [5034:NFKB1_HUMAN ] 7lfc_A_1_B_1 [3112:MLH1_HUMAN ] 7m60_C_1_B_1 [103775:A0A2K3CP55_CHLRE ] 7n6g_V_1_GA_1 [11143 ] 7n8j_A_1_B_1 [9935:TADBP_HUMAN ] 7n9h_A_1_B_1 [8964:T2BB21_MERS ] 7rfx_A_1_B_1 7rfz_A_1_B_1 [8935:T2BB21_MERS ] 7rfy_A_1_B_1 [8952:T2BB21_MERS ] 7rg0_A_1_B_1 [8809:T2BB21_MERS ] 7rg1_A_1_B_1 [8810:T2BB21_MERS ] 7rg2_A_1_B_1 [8811:T2BB21_MERS ] 7rg3_A_1_C_1 [13516:NFKB1_HUMAN ] 7rg4_A_1_B_1 [13517:NFKB1-3_HUMAN ] 7rg5_A_1_B_1 [8320:ORF4B_BCHK5 ] 7rg6_A_1_B_1 [8340:NEIL1_HUMAN ] 7tmx_A_1_B_1 [1243:NEIL3_HUMAN ] 7tmy_A_1_B_1 [2666 ] 7umi_B_1_A_1 [9263:M1LJY4_9FLAV ] 8ech_B_1_A_1 [3204:NS1_PAVHV ] 8f2q_A_1_C_1 [13659:C0LA97_9VIRU ] 8fk3_A_1_B_1 [8501:MATRX_HENDH ] 8fua_A_1_C_1 [8448:MATRX_HENDH ] 8fub_A_1_B_1 [580 ] 8fuc_B_1_C_1 [10869 ] 8fzm_A_1_B_1 8fzm_C_1_D_1 [8794 ] 8g8q_A_1_B_1 [12315:RELB_HUMAN ] 8g8r_A_1_B_1 [12501:F1S861_PIG ] 8g8s_A_1_B_1 [11685 ] 8gai_A_1_B_1 [11684 ] 8gai_C_1_D_1 [13985:HIF1A_HUMAN ] 8he0_A_1_B_1 [5572 ] 8he3_A_1_B_1 [9485:LT_POVK6 ] 8q8k_A_1_C_1 8q8k_B_1_D_1 [10048:VPAP_HCMVA ] 8qxw_A_1_B_1 [11183:VPAP_HCMVA ] 8qxx_A_1_B_1 [16251:A0A2Z4K4X6_9VIRU ] 8sg7_A_1_B_1 [9671:LT_POVJC ] 8sud_A_1_B_1 [1541 ] 8sv0_A_1_C_1 [8805:L7REU2_9POLY ] 8tuq_A_1_B_1 [12503:M4VRX3_9POLY ] 8tur_A_1_B_1 [9544:LT_POVWU ] 8tus_A_1_B_1 [1923 ] 8tut_A_1_B_1 [9545:R4L0R1_9POLY ] 8tuu_A_1_B_1 [33251:RS11_ECO45 ] 8tuv_A_1_C_1 [1950:Q9IIH8_ADEF1 ] 8u36_A_1_B_1 homo [84943:IMA1_YEAST ] 1bk5_A_1_B_1 1bk5_B_1_A_1 [87013:Q6FNI4_CANGA :Q6FX18_CANGA ] 7vpt_A_1_A_3 7vpt_A_2_A_1 7vpt_A_3_A_2 compound [BTB ] 3ukw_A_1_C_1 [3D0 ] 4u5s_A_1_C_1 metal [CA ] 4v3o_B_1_K_1 5mfd_I_1_RA_1 5mfd_J_1_WA_1 precipitant [PEG ] 3wpt_A_1_J_1 4bqk_B_1_K_1 [ACT ] 4pls_B_1_N_1 4pls_C_1_P_1 4v3o_D_1_Q_1 [EDO ] 5mfe_D_1_IA_1 5mff_D_1_T_1 6d7n_A_1_F_1 [GOL ] 5umz_A_1_G_1 [SO4 ] 6wx8_A_1_F_1 6wx8_A_1_G_1 6wx8_C_1_H_1 6wx8_C_1_I_1


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