Summary for the 290-th Site(V) |
PID | QueryLength | FocusSite | TITLE |
2587862 | 967 | 290 V | RecName: Full=Aminopeptidase N ; Short=AP-N; Short=hAPN; EC=3.4.11.2 ;AltName: Full=Alanyl aminopeptidase;AltName: Full=Aminopeptidase M; Short=AP-M;AltName: Full=Microsomal aminopeptidase;AltName: Full=Myeloid plasma membrane glycoprotein CD13;AltName: Full=gp150;AltName: CD_antigen=CD13; |
AC/ID | AC:P15144 ID:AMPN_HUMAN |
Feature Table for 290-th site |
STRAND: REGION: /note="Necessary and sufficient to mediate interaction with HCoV-229E" ECO:0000269|PubMed:8887485" MUTAGEN: /note="DYVEKQAS->QSVEETAQ: No change in receptor activity and HCoV-229E infection." MUTAGEN: /note="DYVEKQAS->QSVNEQAQ: No change in receptor activity and HCoV-229E infection." MUTAGEN: /note="DYVEKQAS->QSVNETAQ: Complete loss of receptor activity and blocks HCoV-229E infection. No loss of enzymatic activity." REGION: /note="Metalloprotease" TOPO_DOM: /note="Extracellular" CHAIN: /note="Aminopeptidase N" /id="PRO_0000095081" |
Percentages of Amino Acids in Homologous Proteins [show alignment] |
V:22% I:21% L:11% S:8% R:7% A:6% K:6% E:4% F:3% D:2% G:2% P:2% T:2% N:1% C:1% Q:1% H:1% M:1% Y:1% |
Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
5lhd | E (beta-strand) | b (buried) | 18.0 |
Predicted Bind Molecules |
hetero:9 |
Templates for 3D complexes |
hetero [38283:SPIKE_CVH22 ] 6atk_A_1_E_1 [38293:SPIKE_CVH22 ] 6atk_B_1_D_1 [38355:SPIKE_CVH22 ] 6atk_C_1_F_1 [38176 ] 6u7e_A_1_C_1 [38175 ] 6u7e_B_1_D_1 [38174 ] 6u7f_A_1_C_1 [38125 ] 6u7f_B_1_D_1 [38107:H1AG31_CVH22 ] 6u7g_A_1_C_1 6u7g_B_1_D_1 |
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