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PID | QueryLength | FocusSite | TITLE |
16000 | 468 | 245 N | RecName: Full=Interleukin-6 receptor subunit alpha ; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA;AltName: Full=IL-6R 1;AltName: Full=Membrane glycoprotein 80; Short=gp80;AltName: CD_antigen=CD126;Contains: RecName: Full=Soluble interleukin-6 receptor subunit alpha ; Short=sIL6R ;Flags: Precursor; |
AC/ID | AC:P08887 ID:IL6RA_HUMAN |
Feature Table for 245-th site |
SITE: /note="Not glycosylated" CARBOHYD: /note="N-linked (GlcNAc...) asparagine" MUTAGEN: /note="N->A: Slightly induces cleavage and sIL6R levels.No effect on IL6R signaling; when associated with A-55, A-93, A-221 and A-350. Loss of cleavage by ADAM17; when associated with A-55, A-93, A-221 and A-350." DOMAIN: /note="Fibronectin type-III 2" CHAIN: /note="Soluble interleukin-6 receptor subunit alpha" /id="PRO_0000450730" TOPO_DOM: /note="Extracellular" CHAIN: /note="Interleukin-6 receptor subunit alpha" /id="PRO_0000010895" |
Percentages of Amino Acids in Homologous Proteins
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S:27% D:21% R:14% K:13% L:7% N:5% F:5% A:1% Q:1% E:1% G:1% I:1% P:1% T:1% V:1% |
Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
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(coil) | e (exposed) | 61.8 |
Predicted Bind Molecules |
hetero:1 homo:1 otherpoly:4 compound:3 |
Templates for 3D complexes |
hetero [3015:IL6RA_HUMAN
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