Summary for the 378-th Site(K) |
PID | QueryLength | FocusSite | TITLE |
1590160 | 425 | 378 K | RecName: Full=Mothers against decapentaplegic homolog 3; Short=MAD homolog 3; Short=Mad3; Short=Mothers against DPP homolog 3; Short=hMAD-3;AltName: Full=JV15-2;AltName: Full=SMAD family member 3; Short=SMAD 3; Short=Smad3; Short=hSMAD3; |
AC/ID | AC:P84022 ID:SMAD3_HUMAN |
Feature Table for 378-th site |
MOD_RES: /note="N6-acetyllysine" MUTAGEN: /note="K->Q: Increased transcriptional activity. No further increase in transcriptional activity with EP300." MUTAGEN: /note="K->R: Greatly reduced acetylation and 85% reduction in transcriptional activity. Completely abolishes acetylation and 97% reduction in transcriptional activity; when associated with R-333; R-341 and R-409." DOMAIN: /note="MH2" CHAIN: /note="Mothers against decapentaplegic homolog 3" /id="PRO_0000090856" |
Percentages of Amino Acids in Homologous Proteins [show alignment] |
K:100% |
Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
1mk2 | (coil) | e (exposed) | 43.9 |
Predicted Bind Molecules |
homo:22 |
Templates for 3D complexes |
homo [51657:SMAD1_HUMAN ] 1khu_A_1_B_1 1khu_C_1_A_1 5zok_A_1_A_2 5zok_A_2_A_4 5zok_A_4_A_1 5zok_C_1_C_5 5zok_C_3_C_1 5zok_C_5_C_3 [48939:SMAD2_HUMAN ] 1khx_A_1_A_2 1khx_A_2_A_3 1khx_A_3_A_1 1u7f_A_1_C_1 1u7v_A_1_B_1 6m64_E_1_A_1 6zvq_A_1_A_2 6zvq_A_2_A_3 6zvq_A_3_A_1 [47381:MAD_DROME ] 3gmj_A_1_A_3 3gmj_A_2_A_1 3gmj_A_3_A_2 3gmj_B_1_C_1 3gmj_D_1_B_1 |
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