Summary for the 279-th Site(R) |
PID | QueryLength | FocusSite | TITLE |
1590160 | 425 | 279 R | RecName: Full=Mothers against decapentaplegic homolog 3; Short=MAD homolog 3; Short=Mad3; Short=Mothers against DPP homolog 3; Short=hMAD-3;AltName: Full=JV15-2;AltName: Full=SMAD family member 3; Short=SMAD 3; Short=Smad3; Short=hSMAD3; |
AC/ID | AC:P84022 ID:SMAD3_HUMAN |
Feature Table for 279-th site |
VARIANT: /note="R -> K (in LDS3; dbSNP:rs387906852)" /id="VAR_067048" REGION: /note="Sufficient for interaction with XPO4" DOMAIN: /note="MH2" CHAIN: /note="Mothers against decapentaplegic homolog 3" /id="PRO_0000090856" |
VARIANT for 279-th site |
R->K LP/P dbSNP:rs3879068 " Loeys-Dietz syndrome 3 (LDS3) " [MIM:613795] |
Percentages of Amino Acids in Homologous Proteins [show alignment] |
R:92% K:8% |
Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
1mk2 | (coil) | e (exposed) | 24.1 |
Predicted Bind Molecules |
hetero:1 |
Templates for 3D complexes |
hetero [58833:SMAD4_HUMAN ] 1u7f_C_1_B_1 |
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