Summary for the 322-nd Site(T)
PID QueryLength FocusSite TITLE
3721728 529 322 T RecName: Full=Importin subunit alpha-1 ;AltName: Full=Karyopherin subunit alpha-2;AltName: Full=RAG cohort protein 1;AltName: Full=SRP1-alpha;
UniProt Information
AC/IDAC:P52292 ID:IMA1_HUMAN
Feature Table for 322-th site REPEAT: /note="ARM 6"
REGION: /note="NLS binding site (minor)"
CHAIN: /note="Importin subunit alpha-1" /id="PRO_0000120722"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
T:37% A:19% S:10% C:7% Q:5% H:5% I:5% V:5% E:3% L:3% K:2%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5h43 T (Hbond turn) e (exposed) 42.9
3D Complex Information
Predicted Bind Molecules
hetero:185 homo:18 compound:5 metal:5 precipitant:9
Templates for 3D complexes
hetero [376 ] 1bk6_A_1_C_1 1bk6_D_1_F_1 [1741:MYC_HUMAN ] 1ee4_A_1_C_1 [1693:MYC_HUMAN ] 1ee4_D_1_F_1 [8066:NUPL_XENLA ] 1ee5_A_1_B_1 [920:TALA_SV40 ] 1ejl_C_1_A_1 [6305:NUPL_XENLA ] 1ejy_B_1_A_1 [16994:P70062_XENLA ] 1g3j_A_1_B_1 [17047:P70062_XENLA ] 1g3j_C_1_D_1 [3635:IMA2_MOUSE ] 1iq1_C_1_A_1 [13359:TF7L2_HUMAN ] 1jdh_A_1_B_1 [15227:TF7L2_HUMAN ] 1jpw_C_1_D_1 [20944:CNBP1_HUMAN ] 1m1e_A_1_B_1 [8521:RB_HUMAN ] 1pjm_B_1_A_1 [9051:IMA2_MOUSE ] 1pjn_B_1_A_1 [11209:TALA_SV40 ] 1q1s_C_1_A_1 [10364:TALA_SV40 ] 1q1t_C_1_A_1 [49489:APC_HUMAN ] 1th1_A_1_C_1 [15510:NUP2_YEAST ] 1un0_A_1_C_1 1un0_B_1_D_1 [14827:NUP50_MOUSE ] 2c1m_A_1_B_1 [15431:NUP2_YEAST ] 2c1t_A_1_C_1 [15430:NUP2_YEAST ] 2c1t_B_1_D_1 [15749:TF7L2_HUMAN ] 2gl7_A_1_B_1 [15744:TF7L2_HUMAN ] 2gl7_D_1_E_1 [21354:PB2_IAVI7 ] 2jdq_A_1_D_1 2jdq_B_1_C_1 [3833 ] 2ynr_A_1_C_1 [4171 ] 2yns_A_1_C_1 2yns_B_1_D_1 [99544:NCBP1_HUMAN ] 3fex_C_1_A_1 3fey_C_1_A_1 [20989:Q9I8N0_XENLA ] 3knd_A_1_B_1 [6059 ] 3l3q_A_1_C_1 [18107:LEF1_MOUSE ] 3oux_A_1_B_1 [4803:PLS4_HUMAN ] 3q5u_A_1_B_1 [29134:NUP50_HUMAN ] 3tj3_A_1_B_1 3tj3_C_1_D_1 [30725 ] 3tpm_A_1_B_1 [11222 ] 3ukw_A_1_B_1 [11248 ] 3ukx_A_1_B_1 [12181:NCBP1_YEAST ] 3uky_A_1_B_1 [10379:NCBP1_MOUSE ] 3ukz_A_1_B_1 3ul0_A_1_B_1 [9202:NUPL_XENLA ] 3ul1_A_1_B_1 4bpl_A_1_B_1 [7913:FEN1_HUMAN ] 3uvu_B_1_A_1 [5351:DDX21_MOUSE ] 3zin_A_1_B_1 [3680 ] 3zio_A_1_B_1 [3682 ] 3zip_A_1_B_1 [3681 ] 3ziq_A_1_C_1 [3103 ] 3zir_A_1_B_1 [8756:TERT_HUMAN ] 4b18_A_1_B_1 [3134 ] 4b8o_A_1_C_1 [4028 ] 4b8p_A_1_C_1 4b8p_B_1_D_1 [8798:VIRD2_AGRT5 ] 4bqk_A_1_D_1 [8533:VIRD2_AGRT5 ] 4bqk_B_1_C_1 [3085 ] 4d49_A_1_C_1 4d49_B_1_D_1 4d49_E_1_G_1 4d49_F_1_H_1 [4706:DUT_HUMAN ] 4mz5_C_1_A_1 [4857:DUT_HUMAN ] 4mz6_C_1_A_1 [11128:RCC1_YEAST ] 4oih_A_1_B_1 [14258:HEH2_YEAST ] 4pvz_A_1_C_1 [14326:HEH2_YEAST ] 4pvz_B_1_D_1 [1398:LT_SV40 ] 4rxh_A_1_B_1 [20174:PB2_I75A3 ] 4uad_A_1_B_1 4uae_A_1_B_1 4uaf_A_1_B_1 [5072:TAF8_HUMAN ] 4wv6_A_1_C_1 [15893:SRC1_YEAST ] 4xzr_B_1_A_1 [11809:PO121_RAT ] 4yi0_A_1_B_1 [6679:NCAP_I34A1 ] 4zdu_A_1_B_1 [3050 ] 5aei_A_1_D_1 5aei_B_1_E_1 5aei_C_1_F_1 5mfj_A_1_D_1 6sa8_A_1_B_1 [3992:VPR_HV1B9 ] 5b56_A_1_C_1 5b56_B_1_D_1 [16087:SART3_HUMAN ] 5ctt_A_1_B_1 [24715:PARP2_HUMAN ] 5d5k_A_1_B_1 [13066:XRCC1_HUMAN ] 5e6q_A_1_B_1 [10164:ERCC5_HUMAN ] 5ekf_C_1_A_1 [8088 ] 5ekg_C_1_A_1 [10999:NUMA1_HUMAN ] 5gxw_A_1_B_1 [48035:ULP1_YEAST ] 5h2w_A_1_B_1 [9758:ULP1_YEAST ] 5h2w_C_1_D_1 5h2x_A_1_B_1 [2823:KAT8_HUMAN ] 5h43_A_1_B_1 [4181 ] 5huw_A_1_C_1 [6512 ] 5huy_A_1_B_1 [3459 ] 5k9s_A_1_C_1 [49447:A0A059PIQ0_AEQVI ] 5mfc_A_1_B_1 5mfc_C_1_D_1 [23992:DECO_LAMBD ] 5mfd_G_1_H_1 [1144 ] 5mfi_A_1_C_1 5mfk_A_1_C_1 [90456:RCC1_YEAST ] 5t94_B_1_A_1 [84627:RCC1_HUMAN ] 5tbk_A_1_J_1 5tbk_B_1_I_1 5tbk_C_1_P_1 5tbk_D_1_O_1 5tbk_E_1_K_1 5tbk_F_1_L_1 5tbk_G_1_M_1 5tbk_H_1_N_1 [2722:MLH1_HUMAN ] 5u5p_C_1_A_1 [4577 ] 5umz_A_1_B_1 [8030 ] 5v5o_A_1_C_1 [8180:Q45VS8_9INFA ] 5v5p_A_1_C_1 [4546 ] 5vqi_A_1_C_1 [11517:DPOLM_HUMAN ] 5w4f_A_1_C_1 [11434:DPOLL_HUMAN ] 5w4g_A_1_B_1 [4386:EBNA1_EBVB9 ] 5wum_A_1_B_1 [2383:EBNA1_EBVB9 ] 5wun_A_1_B_1 [23414:NVJ1_YEAST ] 5xjg_A_1_B_1 5xjg_C_1_D_1 [14009:W_NIPAV ] 6bvv_A_1_B_1 [14010:W_HENDH ] 6bw9_A_1_B_1 6bwa_A_1_B_1 6bwb_A_1_B_1 [9391:TP53B_HUMAN ] 6iu7_A_1_B_1 6iua_A_1_B_1 8hkw_A_1_C_1 8hkw_B_1_D_1 [15782:GOGA2_HUMAN ] 6iw8_B_1_A_1 [12303:GOGA2_HUMAN ] 6iwa_B_1_A_1 [15763:GOGA2_HUMAN ] 6k06_B_1_A_1 [33614:ATG13_YEAST ] 6kbm_A_1_B_1 6kbn_A_1_B_1 6kbn_C_1_D_1 [4723:NIT2_NEUCR ] 6p6a_A_1_B_1 [10200:A0A0B0E960_NEUCS ] 6p6e_A_1_C_1 [3805 ] 6s9l_A_1_C_1 6s9l_B_1_D_1 [3136:MLH1_HUMAN ] 6wba_A_1_B_1 [3125:MLH1_HUMAN ] 6wbb_A_1_B_1 [22668:SOX2_HUMAN ] 6wx7_A_1_B_1 [20573:SOX2_HUMAN ] 6wx8_A_1_B_1 6wx8_C_1_D_1 [22872:SOX2_HUMAN ] 6wx9_A_1_B_1 [9763:HNRPK_HUMAN ] 7cru_B_1_A_1 7cru_D_1_C_1 [9533:TF65_HUMAN ] 7let_A_1_C_1 7leu_A_1_C_1 [9357:TF65_HUMAN ] 7lf4_A_1_F_1 [3645:MLH1_HUMAN ] 7m60_C_1_A_1 [105190:Q6J4H1_CHLRE ] 7n6g_A_1_WF_1 7n6g_N_1_XF_1 [11216 ] 7n8j_A_1_B_1 [10244:TADBP_HUMAN ] 7n9h_A_1_B_1 [9324:T2BB21_MERS ] 7rfx_A_1_B_1 7rfz_A_1_B_1 [9298:T2BB21_MERS ] 7rfy_A_1_B_1 [9125:T2BB21_MERS ] 7rg1_A_1_B_1 [9127:T2BB21_MERS ] 7rg2_A_1_B_1 [9302:T2BB21_MERS ] 7rg3_A_1_B_1 [8676:ORF4B_BCHK5 ] 7rg6_A_1_C_1 [8461:NEIL1_HUMAN ] 7tmx_A_1_C_1 [16210:VAC17_YEAST ] 7ycj_A_1_B_1 [9586:M1LJY4_9FLAV ] 8ech_B_1_A_1 [13813:C0LA97_9VIRU ] 8fk3_A_1_B_1 [8917:MATRX_HENDH ] 8fua_A_1_B_1 [7789:MATRX_HENDH ] 8fuc_B_1_A_1 [11168 ] 8fzm_A_1_B_1 8fzm_C_1_D_1 [491 ] 8g8q_A_1_C_1 [12607:RELB_HUMAN ] 8g8r_A_1_B_1 [12813:F1S861_PIG ] 8g8s_A_1_B_1 [11639 ] 8gai_A_1_B_1 [11741 ] 8gai_C_1_D_1 [14320:HIF1A_HUMAN ] 8he0_A_1_B_1 [9453:LT_POVK6 ] 8q8k_A_1_C_1 8q8k_B_1_D_1 [16475:A0A2Z4K4X6_9VIRU ] 8sg7_A_1_B_1 [1840 ] 8sv0_A_1_B_1 [9122:L7REU2_9POLY ] 8tuq_A_1_B_1 [12815:M4VRX3_9POLY ] 8tur_A_1_B_1 [9869:LT_POVWU ] 8tus_A_1_B_1 [9868:R4L0R1_9POLY ] 8tuu_A_1_B_1 [3167 ] 8tuv_A_1_B_1 [1874:Q9IIH8_ADEF1 ] 8u36_A_1_C_1 homo [63592 ] 4db8_A_1_D_1 4db8_B_1_C_1 4db8_C_1_B_1 4db8_D_1_A_1 [50052 ] 4dba_B_1_A_1 4dba_D_1_C_1 [61065 ] 4pls_A_1_B_1 4pls_D_1_C_1 5mff_B_1_A_1 5mff_C_1_D_1 [63684 ] 4rzp_B_1_A_1 [88503:Q6FNI4_CANGA :Q6FX18_CANGA ] 7vpt_A_1_A_3 7vpt_A_2_A_1 7vpt_A_3_A_2 [86416:IMA1_HUMAN ] 8fzk_A_1_B_1 8fzk_B_1_A_1 8fzk_C_1_D_1 8fzk_D_1_C_1 compound [3D6 ] 4u5l_A_1_B_1 [3D4 ] 4u5n_A_1_B_1 [3D5 ] 4u5o_A_1_B_1 [3D0 ] 4u5s_A_1_B_1 [RH2 ] 4u5v_A_1_B_1 metal [CA ] 5mfd_A_1_Q_1 5mfd_E_1_AA_1 5mfd_J_1_UA_1 5mfg_D_1_R_1 [NA ] 8ru4_A_1_J_1 precipitant [URE ] 3bct_A_1_J_1 3bct_A_2_J_2 4ev8_A_1_I_1 4ev9_A_1_H_1 4eva_A_1_J_1 4eva_B_1_WA_1 4evt_A_1_ZA_1 [PG4 ] 6s9m_D_1_GA_1 [EDO ] 8qzn_A_1_U_1


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