Summary for the 191-st Site(G)
PID QueryLength FocusSite TITLE
3721728 529 191 G RecName: Full=Importin subunit alpha-1 ;AltName: Full=Karyopherin subunit alpha-2;AltName: Full=RAG cohort protein 1;AltName: Full=SRP1-alpha;
UniProt Information
AC/IDAC:P52292 ID:IMA1_HUMAN
Feature Table for 191-th site REPEAT: /note="ARM 3"
REGION: /note="NLS binding site (major)"
CHAIN: /note="Importin subunit alpha-1" /id="PRO_0000120722"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
G:37% V:22% K:10% E:7% A:6% C:3% Q:3% H:3% I:3% S:3% L:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5h43 T (Hbond turn) e (exposed) 41.7
3D Complex Information
Predicted Bind Molecules
hetero:209 homo:9 compound:2 metal:3 precipitant:5
Templates for 3D complexes
hetero [631 ] 1bk6_A_1_B_1 1bk6_D_1_E_1 [1739:MYC_HUMAN ] 1ee4_A_1_B_1 1ee4_D_1_E_1 [8066:NUPL_XENLA ] 1ee5_A_1_B_1 [920:TALA_SV40 ] 1ejl_C_1_B_1 [6305:NUPL_XENLA ] 1ejy_B_1_A_1 [16994:P70062_XENLA ] 1g3j_A_1_B_1 [17047:P70062_XENLA ] 1g3j_C_1_D_1 [42323:CADH1_MOUSE ] 1i7w_A_1_B_1 1i7w_C_1_D_1 [39471:CADH1_MOUSE ] 1i7x_A_1_B_1 [39472:CADH1_MOUSE ] 1i7x_C_1_D_1 [3573:IMA2_MOUSE ] 1iq1_C_1_B_1 [13359:TF7L2_HUMAN ] 1jdh_A_1_B_1 [15227:TF7L2_HUMAN ] 1jpw_A_1_B_1 1jpw_C_1_D_1 1jpw_E_1_F_1 [19611:CNBP1_MOUSE ] 1luj_A_1_B_1 [8521:RB_HUMAN ] 1pjm_B_1_A_1 [9051:IMA2_MOUSE ] 1pjn_B_1_A_1 [11210:TALA_SV40 ] 1q1s_C_1_B_1 [10563:TALA_SV40 ] 1q1t_C_1_B_1 [6013:APC_HUMAN ] 1t08_A_1_C_1 [49489:APC_HUMAN ] 1th1_A_1_C_1 1th1_B_1_D_1 [17381:APC_HUMAN ] 1v18_A_1_B_1 [15749:TF7L2_HUMAN ] 2gl7_A_1_B_1 [15744:TF7L2_HUMAN ] 2gl7_D_1_E_1 [21354:PB2_IAVI7 ] 2jdq_A_1_D_1 2jdq_B_1_C_1 [5974:ANDR_HUMAN ] 3btr_A_1_B_1 [99544:NCBP1_HUMAN ] 3fex_C_1_A_1 3fey_C_1_A_1 [20989:Q9I8N0_XENLA ] 3knd_A_1_B_1 [5540 ] 3l3q_A_1_B_1 [2999:CLIC4_HUMAN ] 3oqs_B_1_A_1 [4704:XRCC5_HUMAN ] 3rz9_A_1_B_1 [9518:XRCC6_HUMAN ] 3rzx_A_1_B_1 [29134:NUP50_HUMAN ] 3tj3_A_1_B_1 3tj3_C_1_D_1 [30725 ] 3tpm_A_1_B_1 [78846:NR5A2_HUMAN ] 3tx7_A_1_B_1 [11222 ] 3ukw_A_1_B_1 [11248 ] 3ukx_A_1_B_1 [12181:NCBP1_YEAST ] 3uky_A_1_B_1 [10379:NCBP1_MOUSE ] 3ukz_A_1_B_1 3ul0_A_1_B_1 [9202:NUPL_XENLA ] 3ul1_A_1_B_1 4bpl_A_1_B_1 [7913:FEN1_HUMAN ] 3uvu_B_1_A_1 [4271:Q9WCF8_9VIRU ] 3ve6_A_1_B_1 [4935:DDX21_MOUSE ] 3zin_A_1_C_1 [3678 ] 3zio_A_1_C_1 [8756:TERT_HUMAN ] 4b18_A_1_B_1 [3133 ] 4b8o_A_1_B_1 [4100 ] 4ba3_A_1_B_1 [8798:VIRD2_AGRT5 ] 4bqk_A_1_D_1 [8533:VIRD2_AGRT5 ] 4bqk_B_1_C_1 [11497:Q68SX0_BFDV ] 4htv_A_1_B_1 [4858:DUT_HUMAN ] 4mz5_C_1_B_1 [4894:DUT_HUMAN ] 4mz6_C_1_B_1 [11128:RCC1_YEAST ] 4oih_A_1_B_1 [14258:HEH2_YEAST ] 4pvz_A_1_C_1 [14326:HEH2_YEAST ] 4pvz_B_1_D_1 [1345:LT_SV40 ] 4rxh_A_1_C_1 [20174:PB2_I75A3 ] 4uad_A_1_B_1 4uaf_A_1_B_1 [5149:TAF8_HUMAN ] 4wv6_A_1_B_1 [15893:SRC1_YEAST ] 4xzr_B_1_A_1 [11809:PO121_RAT ] 4yi0_A_1_B_1 [3050 ] 5aei_A_1_D_1 5aei_B_1_E_1 5aei_C_1_F_1 6sa8_A_1_B_1 [3992:VPR_HV1B9 ] 5b56_A_1_E_1 5b56_B_1_F_1 [16087:SART3_HUMAN ] 5ctt_A_1_B_1 [24715:PARP2_HUMAN ] 5d5k_A_1_B_1 [13066:XRCC1_HUMAN ] 5e6q_A_1_B_1 [10296:ERCC5_HUMAN ] 5ekf_C_1_B_1 [8354 ] 5ekg_C_1_B_1 [13085:B6VDJ7_9FLAV ] 5fc8_B_1_A_1 [10999:NUMA1_HUMAN ] 5gxw_A_1_B_1 [48035:ULP1_YEAST ] 5h2w_A_1_B_1 [9758:ULP1_YEAST ] 5h2w_C_1_D_1 5h2x_A_1_B_1 [5604:KAT8_HUMAN ] 5h43_A_1_C_1 [13108:POLG_DEN2P ] 5hhg_B_1_A_1 [4190 ] 5huw_A_1_B_1 [6266 ] 5huy_A_1_C_1 [3459 ] 5k9s_A_1_B_1 [6267 ] 5klr_A_1_B_1 [6630 ] 5klt_A_1_B_1 [49447:A0A059PIQ0_AEQVI ] 5mfc_A_1_B_1 5mfc_C_1_D_1 [23992:DECO_LAMBD ] 5mfd_A_1_B_1 5mfd_C_1_D_1 5mfd_E_1_F_1 5mfd_G_1_H_1 [1185 ] 5mfe_A_1_E_1 [2532 ] 5mfh_A_1_E_1 5mfh_C_1_F_1 [5999 ] 5svz_A_1_B_1 [90456:RCC1_YEAST ] 5t94_B_1_A_1 [84627:RCC1_HUMAN ] 5tbk_A_1_J_1 5tbk_E_1_K_1 5tbk_G_1_M_1 5tbk_H_1_N_1 [3003:MLH1_HUMAN ] 5u5p_C_1_B_1 [3589:PMS2_HUMAN ] 5u5r_A_1_B_1 [4742 ] 5umz_A_1_C_1 [8029 ] 5v5o_A_1_B_1 [4476 ] 5vqi_A_1_B_1 [13605:POLG_ZIKV ] 5w41_A_1_B_1 [6257 ] 5w4e_A_1_B_1 [11435:DPOLM_HUMAN ] 5w4f_A_1_B_1 [11434:DPOLL_HUMAN ] 5w4g_A_1_B_1 [9655:EBNA5_EBVB9 ] 5x8n_A_1_B_1 [11794:RANB3_HUMAN ] 5xzx_A_1_B_1 [14009:W_NIPAV ] 6bvv_A_1_B_1 [14011:W_NIPAV ] 6bw0_B_1_A_1 6bw1_B_1_A_1 [14010:W_HENDH ] 6bw9_A_1_B_1 6bwa_A_1_B_1 6bwb_A_1_B_1 [9391:TP53B_HUMAN ] 6iu7_A_1_B_1 6iua_A_1_B_1 8hkw_A_1_D_1 8hkw_B_1_C_1 [15782:GOGA2_HUMAN ] 6iw8_B_1_A_1 [12303:GOGA2_HUMAN ] 6iwa_B_1_A_1 [15763:GOGA2_HUMAN ] 6k06_B_1_A_1 [1750 ] 6mjl_A_1_B_1 [4546:NIT2_NEUCR ] 6p6a_A_1_C_1 [10068:A0A0B0E960_NEUCS ] 6p6e_A_1_B_1 [3805 ] 6s9l_A_1_C_1 6s9l_B_1_D_1 [3135:MLH1_HUMAN ] 6wba_A_1_C_1 [3361:MLH1_HUMAN ] 6wbb_A_1_C_1 [3526:MLH1_HUMAN ] 6wbc_A_1_B_1 [22668:SOX2_HUMAN ] 6wx7_A_1_B_1 [20573:SOX2_HUMAN ] 6wx8_A_1_B_1 6wx8_C_1_D_1 [22872:SOX2_HUMAN ] 6wx9_A_1_B_1 [9763:HNRPK_HUMAN ] 7cru_B_1_A_1 7cru_D_1_C_1 [10818:KDM1A_HUMAN ] 7jjl_A_1_B_1 7jjm_B_1_A_1 [10823:KDM1A_HUMAN ] 7jk7_B_1_A_1 [5397 ] 7jvo_A_1_B_1 [2931:C0LA97_9VIRU ] 7l04_B_1_A_1 [4934:NFKB1_HUMAN ] 7leq_A_1_B_1 [5441:NFKB1_HUMAN ] 7let_A_1_B_1 [9359:TF65_HUMAN ] 7leu_A_1_B_1 [5497:NFKB1_HUMAN ] 7lf4_A_1_B_1 7lf4_C_1_E_1 [5090:NFKB1_HUMAN ] 7lfc_A_1_B_1 [3393:MLH1_HUMAN ] 7m60_C_1_B_1 [105736:A0A2K3CP55_CHLRE ] 7n6g_Q_1_HA_1 7n6g_V_1_GA_1 [11216 ] 7n8j_A_1_B_1 [10244:TADBP_HUMAN ] 7n9h_A_1_B_1 [9324:T2BB21_MERS ] 7rfx_A_1_B_1 7rfz_A_1_B_1 [9298:T2BB21_MERS ] 7rfy_A_1_B_1 [9312:T2BB21_MERS ] 7rg0_A_1_B_1 [9125:T2BB21_MERS ] 7rg1_A_1_B_1 [9127:T2BB21_MERS ] 7rg2_A_1_B_1 [9124:T2BB21_MERS ] 7rg3_A_1_C_1 [13901:NFKB1_HUMAN ] 7rg4_A_1_B_1 [13902:NFKB1-3_HUMAN ] 7rg5_A_1_B_1 [8685:ORF4B_BCHK5 ] 7rg6_A_1_B_1 [105734:A0A2K3CP55_CHLRE ] 7sqc_BE_1_IJ_1 7sqc_DE_1_JJ_1 7sqc_FE_1_KJ_1 [8702:NEIL1_HUMAN ] 7tmx_A_1_B_1 [1457:NEIL3_HUMAN ] 7tmy_A_1_B_1 [3045 ] 7umi_B_1_A_1 [3524:NS1_PAVHV ] 8f2q_A_1_C_1 [13813:C0LA97_9VIRU ] 8fk3_A_1_B_1 [8395:MATRX_HENDH ] 8fua_A_1_C_1 [8869:MATRX_HENDH ] 8fub_A_1_B_1 [752 ] 8fuc_B_1_C_1 [11168 ] 8fzm_A_1_B_1 8fzm_C_1_D_1 [9109 ] 8g8q_A_1_B_1 [12607:RELB_HUMAN ] 8g8r_A_1_B_1 [12813:F1S861_PIG ] 8g8s_A_1_B_1 [11639 ] 8gai_A_1_B_1 [11741 ] 8gai_C_1_D_1 [14320:HIF1A_HUMAN ] 8he0_A_1_B_1 [5980 ] 8he3_A_1_B_1 [9453:LT_POVK6 ] 8q8k_A_1_C_1 8q8k_B_1_D_1 [10073:VPAP_HCMVA ] 8qxw_A_1_B_1 [11240:VPAP_HCMVA ] 8qxx_A_1_B_1 [16475:A0A2Z4K4X6_9VIRU ] 8sg7_A_1_B_1 [10005:LT_POVJC ] 8sud_A_1_B_1 [1839 ] 8sv0_A_1_C_1 [9122:L7REU2_9POLY ] 8tuq_A_1_B_1 [12815:M4VRX3_9POLY ] 8tur_A_1_B_1 [9869:LT_POVWU ] 8tus_A_1_B_1 [2370 ] 8tut_A_1_B_1 [9868:R4L0R1_9POLY ] 8tuu_A_1_B_1 [33651:RS11_ECO45 ] 8tuv_A_1_C_1 [1568:Q9IIH8_ADEF1 ] 8u36_A_1_B_1 [6449:POLG_DEN1W ] 8vpr_A_1_B_1 [13202:A0A7L4WR04_9FLAV ] 8vpu_A_1_B_1 homo [61065 ] 4plr_A_1_B_1 4plr_B_1_A_1 5mff_A_1_B_1 5mff_C_1_D_1 5mfg_B_1_A_1 6s9p_B_1_A_1 [88503:Q6FNI4_CANGA :Q6FX18_CANGA ] 7vpt_A_1_A_3 7vpt_A_2_A_1 7vpt_A_3_A_2 compound [GLC ] 8ru4_A_1_D_1 8ru4_B_1_M_1 metal [CA ] 4plr_A_1_F_1 4plr_B_1_J_1 5mfd_J_1_WA_1 precipitant [URE ] 4eva_A_1_W_1 4evt_A_1_BA_1 4evt_A_1_Z_1 [ACT ] 4rv1_A_1_G_1 [EDO ] 5mfe_D_1_IA_1


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