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| PID | QueryLength | FocusSite | TITLE |
| 31440 | 4405 | 1638 T | RecName: Full=Replicase polyprotein 1a; Short=pp1a;AltName: Full=ORF1a polyprotein;Contains: RecName: Full=Host translation inhibitor nsp1; AltName: Full=Leader protein; AltName: Full=Non-structural protein 1; Short=nsp1;Contains: RecName: Full=Non-structural protein 2; Short=nsp2; AltName: Full=p65 homolog;Contains: RecName: Full=Papain-like protease nsp3 ; EC=3.4.19.12 ; EC=3.4.22.-; AltName: Full=Non-structural protein 3; Short=nsp3; AltName: Full=PL2-PRO; AltName: Full=Papain-like proteinase; Short=PL-PRO;Contains: RecName: Full=Non-structural protein 4; Short=nsp4;Contains: RecName: Full=3C-like proteinase nsp5; Short=3CL-PRO; Short=3CLp; EC=3.4.22.69; AltName: Full=Main protease; Short=Mpro ; AltName: Full=Non-structural protein 5; Short=nsp5; AltName: Full=SARS coronavirus main proteinase;Contains: RecName: Full=Non-structural protein 6; Short=nsp6;Contains: RecName: Full=Non-structural protein 7; Short=nsp7;Contains: RecName: Full=Non-structural protein 8; Short=nsp8;Contains: RecName: Full=RNA-capping enzyme subunit nsp9; AltName: Full=Non-structural protein 9; Short=nsp9; EC=2.7.7.50 ;Contains: RecName: Full=Non-structural protein 10; Short=nsp10; AltName: Full=Growth factor-like peptide; Short=GFL;Contains: RecName: Full=Non-structural protein 11; Short=nsp11; |
| AC/ID | AC:P0DTC1 ID:R1A_SARS2 |
| Feature Table for 1638-th site |
MUTAGEN: /note="T->A: Partial loss of ubiquitin cleavage in vitro; no effect on ISG15 cleavage in vitro." MUTAGEN: /note="T->L: Increased cleavage of ubiquitin in vitro; no effect on ISG15 cleavage in vitro." DOMAIN: /note="Peptidase C16" CHAIN: /note="Papain-like protease nsp3" /id="PRO_0000449637" TOPO_DOM: /note="Cytoplasmic" CHAIN: /note="Replicase polyprotein 1a" /id="PRO_0000449634" |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
|
F:25% D:18% L:13% A:12% V:12% K:8% S:5% T:4% I:3% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 6wuu |
(coil) | e (exposed) | 77.3 |
| Predicted Bind Molecules |
| hetero:2 homo:4 compound:4 metal:1 precipitant:8 |
| Templates for 3D complexes |
|
hetero [39960:ISG15_HUMAN
] 7rbs_I_1_J_1 [19611:UBB_HUMAN
] 7uv5_A_1_C_1
homo [72168:R1AB_SARS2
] 6xg3_A_1_A_2 6xg3_A_2_A_1 7cjd_A_1_D_1 8iho_A_1_B_1
compound [A5I ] 7qch_A_1_B_1 [A6Q ] 7qci_A_1_B_1 [A4O ] 7qcj_A_1_F_1 [A7L ] 7qck_A_1_B_1
metal [CL ] 7sqe_C_1_S_1
precipitant [EDO ] 7d7k_A_1_I_1 7rzc_B_1_L_1 7rzc_C_1_V_1 7sqe_B_1_L_1 [BO3 ] 7lbs_A_1_G_1 7llf_A_1_F_1 [GOL ] 7lbs_B_1_M_1 [SO4 ] 7nt4_B_1_T_1
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Summary for the 1638-th Site(T)