Summary for the 178-th Site(M)

PID QueryLength FocusSite TITLE
2993159 296 178 M RecName: Full=Myeloid differentiation primary response protein MyD88 ;
UniProt Information
AC/IDAC:Q99836 ID:MYD88_HUMAN
Feature Table for 178-th site VARIANT: /note="M -> I (found in hematological malignancies; uncertain significance; somatic mutation; no effect on NF- kappaB complex activation; dbSNP:rs41285117)" ECO:0000269|PubMed:24316379" /id="VAR_072896"
HELIX:
DOMAIN: /note="TIR"
VAR_SEQ: /note="HMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSI ASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPS ILRFITVCDYTNPCTKSWFWTRLAKALSLP -> AAGWWWLSLMITCRARNVTSRPNLH SASLQVPIRSD (in isoform 3 and isoform 4)" /id="VSP_043500"
CHAIN: /note="Myeloid differentiation primary response protein MyD88" /id="PRO_0000096666"
VARIANT for 178-th site M->I US dbSNP:rs4128511 " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
M:39% L:34% I:19% T:9% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
2js7 H (alpha-helix) b (buried) 0.0


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