Summary for the 288-th Site(R)

PID QueryLength FocusSite TITLE
2993159 296 288 R RecName: Full=Myeloid differentiation primary response protein MyD88 ;
UniProt Information
AC/IDAC:Q99836 ID:MYD88_HUMAN
Feature Table for 288-th site MUTAGEN: /note="R->A: Slightly reduced activity, and reduced interaction with TIRAP. Strongly reduced interaction with TIRAP; when associated with A-196."
DOMAIN: /note="TIR"
VAR_SEQ: /note="HMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSI ASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPS ILRFITVCDYTNPCTKSWFWTRLAKALSLP -> AAGWWWLSLMITCRARNVTSRPNLH SASLQVPIRSD (in isoform 3 and isoform 4)" /id="VSP_043500"
CHAIN: /note="Myeloid differentiation primary response protein MyD88" /id="PRO_0000096666"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
R:50% N:23% K:17% Q:10% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
2js7 H (alpha-helix) e (exposed) 55.3


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