Summary for the 280-th Site(C)

PID QueryLength FocusSite TITLE
2993159 296 280 C RecName: Full=Myeloid differentiation primary response protein MyD88 ;
UniProt Information
AC/IDAC:Q99836 ID:MYD88_HUMAN
Feature Table for 280-th site MUTAGEN: /note="C->S: Abolished interaction with E.coli TcpC without affecting ability to promote Toll-like receptor (TLR)- mediated cytokine production; when associated with S-203."
HELIX:
DOMAIN: /note="TIR"
VAR_SEQ: /note="HMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSI ASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPS ILRFITVCDYTNPCTKSWFWTRLAKALSLP -> AAGWWWLSLMITCRARNVTSRPNLH SASLQVPIRSD (in isoform 3 and isoform 4)" /id="VSP_043500"
CHAIN: /note="Myeloid differentiation primary response protein MyD88" /id="PRO_0000096666"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
C:27% K:11% L:9% A:8% T:8% V:8% W:7% G:6% E:5% Y:3% R:1% N:1% D:1% Q:1% I:1% F:1% P:1% S:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
2js7 T (Hbond turn) e (exposed) 85.3


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