Summary for the 281-st Site(T)
PID QueryLength FocusSite TITLE
2993159 296 281 T RecName: Full=Myeloid differentiation primary response protein MyD88 ;
UniProt Information
AC/IDAC:Q99836 ID:MYD88_HUMAN
Feature Table for 281-th site VARIANT: /note="T -> P (found in hematological malignancies; uncertain significance; somatic mutation; no effect on NF- kappaB complex activation)" /id="VAR_073263"
HELIX:
DOMAIN: /note="TIR"
VAR_SEQ: /note="HMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSI ASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPS ILRFITVCDYTNPCTKSWFWTRLAKALSLP -> AAGWWWLSLMITCRARNVTSRPNLH SASLQVPIRSD (in isoform 3 and isoform 4)" /id="VSP_043500"
CHAIN: /note="Myeloid differentiation primary response protein MyD88" /id="PRO_0000096666"
VARIANT for 281-th site T->P US " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
T:30% Q:29% G:15% S:11% L:8% H:3% A:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
2js7 T (Hbond turn) b (buried) 12.3


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