Summary for the 209-th Site(S)
PID QueryLength FocusSite TITLE
2993159 296 209 S RecName: Full=Myeloid differentiation primary response protein MyD88 ;
UniProt Information
AC/IDAC:Q99836 ID:MYD88_HUMAN
Feature Table for 209-th site VARIANT: /note="S -> R (found in hematological malignancies; uncertain significance; somatic mutation; constitutively activates NF-kappaB complex activation)" /id="VAR_073259"
HELIX:
DOMAIN: /note="TIR"
VAR_SEQ: /note="HMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSI ASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPS ILRFITVCDYTNPCTKSWFWTRLAKALSLP -> AAGWWWLSLMITCRARNVTSRPNLH SASLQVPIRSD (in isoform 3 and isoform 4)" /id="VSP_043500"
CHAIN: /note="Myeloid differentiation primary response protein MyD88" /id="PRO_0000096666"
VARIANT for 209-th site S->R US " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
S:22% A:16% Q:16% I:15% V:12% H:7% L:5% D:4% G:2%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
2js7 G (3/10-helix) e (exposed) 58.6


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