Summary for the 219-th Site(M)

PID QueryLength FocusSite TITLE
2993159 296 219 M RecName: Full=Myeloid differentiation primary response protein MyD88 ;
UniProt Information
AC/IDAC:Q99836 ID:MYD88_HUMAN
Feature Table for 219-th site VARIANT: /note="M -> T (found in hematological malignancies; uncertain significance; somatic mutation; constitutively activates NF-kappaB complex activation)" /id="VAR_073260"
STRAND:
DOMAIN: /note="TIR"
VAR_SEQ: /note="HMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSI ASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPS ILRFITVCDYTNPCTKSWFWTRLAKALSLP -> AAGWWWLSLMITCRARNVTSRPNLH SASLQVPIRSD (in isoform 3 and isoform 4)" /id="VSP_043500"
CHAIN: /note="Myeloid differentiation primary response protein MyD88" /id="PRO_0000096666"
VARIANT for 219-th site M->T US " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
T:33% L:21% M:20% V:17% A:1% R:1% N:1% D:1% E:1% G:1% I:1% K:1% P:1% S:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
2js7 E (beta-strand) b (buried) 0.0


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