Summary for the 179-th Site(I)
PID QueryLength FocusSite TITLE
2993159 296 179 I RecName: Full=Myeloid differentiation primary response protein MyD88 ;
UniProt Information
AC/IDAC:Q99836 ID:MYD88_HUMAN
Feature Table for 179-th site MUTAGEN: /note="I->N: In Pococurante (Poc); abolished MYD88- dependent sensing of most Toll-like receptor (TLR) ligands."
HELIX:
DOMAIN: /note="TIR"
VAR_SEQ: /note="HMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSI ASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPS ILRFITVCDYTNPCTKSWFWTRLAKALSLP -> AAGWWWLSLMITCRARNVTSRPNLH SASLQVPIRSD (in isoform 3 and isoform 4)" /id="VSP_043500"
CHAIN: /note="Myeloid differentiation primary response protein MyD88" /id="PRO_0000096666"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
V:44% L:27% I:18% M:5% A:4%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
2js7 H (alpha-helix) b (buried) 6.4


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