Summary for the 205-th Site(W)
PID QueryLength FocusSite TITLE
2993159 296 205 W RecName: Full=Myeloid differentiation primary response protein MyD88 ;
UniProt Information
AC/IDAC:Q99836 ID:MYD88_HUMAN
Feature Table for 205-th site VARIANT: /note="W -> R (found in hematological malignancies; uncertain significance; somatic mutation)" /id="VAR_073256"
DOMAIN: /note="TIR"
VAR_SEQ: /note="HMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSI ASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPS ILRFITVCDYTNPCTKSWFWTRLAKALSLP -> AAGWWWLSLMITCRARNVTSRPNLH SASLQVPIRSD (in isoform 3 and isoform 4)" /id="VSP_043500"
CHAIN: /note="Myeloid differentiation primary response protein MyD88" /id="PRO_0000096666"
VARIANT for 205-th site W->R US " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
V:22% W:20% I:14% F:10% S:9% T:6% R:5% Q:4% A:1% N:1% D:1% E:1% G:1% L:1% K:1% P:1% Y:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
2js7 (coil) b (buried) 17.5
3D Complex Information
Predicted Bind Molecules
homo:14
Templates for 3D complexes
homo [42153:TLR2_HUMAN ] 1fyw_A_1_A_2 1fyw_A_2_A_1 1fyx_A_1_A_2 1fyx_A_2_A_1 [37648:TLR2_HUMAN ] 1o77_A_1_B_1 [44936:TLR6_HUMAN ] 4om7_A_1_B_1 [36901:TIRAP_HUMAN ] 5uzb_A_1_N_1 5uzb_B_1_N_1 5uzb_C_1_B_1 5uzb_D_1_B_1 5uzb_E_1_L_1 5uzb_F_1_L_1 5uzb_G_1_J_1 5uzb_H_1_J_1


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