Summary for the 86-th Site(Q)
PID QueryLength FocusSite TITLE
2931865 365 86 Q RecName: Full=HLA class I histocompatibility antigen, A alpha chain;AltName: Full=Human leukocyte antigen A; Short=HLA-A;Flags: Precursor;
UniProt Information
AC/IDAC:P04439 ID:HLAA_HUMAN
Feature Table for 86-th site VARIANT: /note="Q -> E (in allele A*23:01, allele 24:02 and allele A*80:01)" ECO:0000269|PubMed:8188325, ECO:0000269|PubMed:8284791, ECO:0000269|PubMed:9349616" /id="VAR_082330"
VARIANT: /note="Q -> G (in allele A*02:01 and allele A*02:05; requires 2 nucleotide substitutions)" ECO:0000269|PubMed:2982951, ECO:0000269|PubMed:3496393, ECO:0000269|PubMed:7836067" /id="VAR_082331"
VARIANT: /note="Q -> L (in alleles A*29:02 and allele A*43:01)" ECO:0000269|PubMed:1782566" /id="VAR_082332"
VARIANT: /note="Q -> R (in allele A*25:01, allele A*26:01, allele A*33:01, allele A*34:01, allele A*66:01, allele A*68:01 and allele A*69:01)" ECO:0000269|PubMed:2320591, ECO:0000269|PubMed:2478623, ECO:0000269|PubMed:3877632, ECO:0000269|PubMed:8026990, ECO:0000269|PubMed:8475492" /id="VAR_082333"
HELIX:
REGION: /note="Alpha-1"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="HLA class I histocompatibility antigen, A alpha chain" /id="PRO_0000018815"
VARIANT for 86-th site Q->E LB/B " -"
Q->G LB/B " -"
Q->L LB/B " -"
Q->R LB/B " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
R:35% K:20% Q:13% N:9% G:8% E:7% T:3% H:1% L:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
6o9c H (alpha-helix) e (exposed) 54.1
3D Complex Information
Predicted Bind Molecules
hetero:45 precipitant:2
Templates for 3D complexes
hetero [2739:NEF_HV1Z6 ] 1qvo_A_1_C_1 1qvo_D_1_F_1 3rl2_A_1_C_1 [1605:NCAP_CVHSA ] 1x7q_A_1_C_1 7wkj_A_1_C_1 [1725:MYPR_HUMAN ] 2xpg_A_1_C_1 [2108:Q9YV12_9HIV1 ] 3rl1_A_1_C_1 6id4_E_1_I_1 8erx_A_1_C_1 [3449:R4P6M5_9INFA ] 4mj5_A_1_C_1 [3131:R4X2K3_9INFA ] 4mj6_A_1_C_1 [2133:A14_VACCW ] 4n8v_C_1_E_1 4n8v_F_1_H_1 [2411 ] 5grd_A_1_C_1 [48569:A0A087WSZ9_HUMAN :K7N5N2_HUMAN ] 5wkf_A_1_D_1 5wkf_F_1_I_1 5wkh_A_1_D_1 5wkh_F_1_I_1 [1893 ] 6j29_A_1_B_1 [2061 ] 6j2a_A_1_C_1 [469 ] 6jp3_A_1_C_1 [49570 ] 7ow5_A_1_D_1 [49599 ] 7ow6_A_1_D_1 [49596 ] 7pb2_A_1_D_1 7pb2_F_1_I_1 [50433 ] 7rrg_A_1_C_2 [2045:PK3CA_HUMAN ] 7rrg_A_1_E_1 [2971:NS1_INBSJ ] 7s8s_A_1_C_1 [1943:NCAP_I46A1 ] 7uc5_A_1_C_1 7uc5_D_1_F_1 [48734 ] 8i5c_A_1_D_1 8i5c_EA_1_HA_1 8i5c_F_1_I_1 8i5c_JA_1_MA_1 8i5c_K_1_N_1 8i5c_OA_1_RA_1 8i5c_P_1_S_1 8i5c_TA_1_WA_1 8i5c_U_1_X_1 8i5c_Z_1_CA_1 [47796 ] 8i5d_C_1_A_1 [48503 ] 8wte_H_1_F_1 8wul_L_1_C_1 [59962 ] 8wte_H_1_G_1 8wul_L_1_D_1 precipitant [SO4 ] 1x7q_A_1_E_1 2hn7_A_1_F_1


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