Summary for the 33-rd Site(F)
PID QueryLength FocusSite TITLE
2931865 365 33 F RecName: Full=HLA class I histocompatibility antigen, A alpha chain;AltName: Full=Human leukocyte antigen A; Short=HLA-A;Flags: Precursor;
UniProt Information
AC/IDAC:P04439 ID:HLAA_HUMAN
Feature Table for 33-th site VARIANT: /note="F -> S (in allele A*23:01, allele A*24:02 and allele A*30:01; dbSNP:rs2075684)" ECO:0000269|PubMed:2478623, ECO:0000269|PubMed:7871528, ECO:0000269|PubMed:9349616" /id="VAR_082320"
VARIANT: /note="F -> T (in allele A*29:02, allele A*31:01 and allele A*33:01; requires 2 nucleotide substitutions)" ECO:0000269|PubMed:1782566, ECO:0000269|PubMed:2478623, ECO:0000269|PubMed:8795145" /id="VAR_082321"
VARIANT: /note="F -> Y (in allele A*02:05, allele A*11:01, allele A*25:01, allele A*26:01, allele A*34:01, allele A*43:01, allele A*66:01, allele A*68:01 and allele A*69:01; dbSNP:rs2075684)" ECO:0000269|PubMed:2320591, ECO:0000269|PubMed:2437024, ECO:0000269|PubMed:2460344, ECO:0000269|PubMed:3496393, ECO:0000269|PubMed:3877632, ECO:0000269|PubMed:8016845, ECO:0000269|PubMed:8026990, ECO:0000269|PubMed:8475492" /id="VAR_082322"
STRAND:
REGION: /note="Alpha-1"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="HLA class I histocompatibility antigen, A alpha chain" /id="PRO_0000018815"
VARIANT for 33-th site F->S LB/B dbSNP:rs2075684 " -"
F->T LB/B " -"
F->Y LB/B dbSNP:rs2075684 " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
F:23% Y:22% L:18% V:7% R:6% H:6% I:6% S:6% Q:2% E:2% D:1% T:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
6o9c E (beta-strand) b (buried) 3.3
3D Complex Information
Predicted Bind Molecules
hetero:171
Templates for 3D complexes
hetero [22561:B2MG_HUMAN ] 1q94_A_1_B_1 1q94_D_1_E_1 1qvo_A_1_B_1 1qvo_D_1_E_1 1x7q_A_1_B_1 2hn7_A_1_B_1 2xpg_A_1_B_1 3rl1_A_1_B_1 3rl2_A_1_B_1 4mj5_A_1_B_1 4mj6_A_1_B_1 4n8v_C_1_D_1 4n8v_F_1_G_1 4uq2_A_1_B_1 4uq2_C_1_D_1 5grd_A_1_B_1 5grg_A_1_B_1 5gsd_A_1_B_1 5wjl_A_1_B_1 5wjl_D_1_E_1 5wjl_G_1_H_1 5wjn_A_1_B_1 5wjn_D_1_E_1 5wjn_G_1_H_1 5wkf_A_1_B_1 5wkf_F_1_G_1 5wkh_A_1_B_1 5wkh_F_1_G_1 6id4_A_1_B_1 6id4_E_1_F_1 6j1v_A_1_B_1 6j1w_A_1_C_1 6j29_A_1_C_1 6j2a_A_1_B_1 6joz_A_1_B_1 6jp3_A_1_B_1 6o9b_A_1_B_1 6o9c_A_1_B_1 7l1b_A_1_B_1 7l1c_A_1_B_1 7l1d_A_2_B_2 7m8t_A_1_B_1 7mle_A_1_B_1 7ow3_A_1_B_1 7ow3_D_1_E_1 7ow3_G_1_H_1 7ow3_J_1_K_1 7ow4_A_1_B_1 7ow4_D_1_E_1 7ow4_G_1_H_1 7ow4_J_1_K_1 7ow5_A_1_B_1 7ow6_A_1_B_1 7pb2_A_1_B_1 7pb2_F_1_G_1 7rrg_A_1_B_1 7s8q_A_1_B_1 7s8q_D_1_E_1 7s8r_A_1_B_1 7s8r_D_1_E_1 7s8s_A_1_B_1 7uc5_A_1_B_1 7uc5_D_1_E_1 7wkj_A_1_B_1 8dvg_A_1_B_1 8erx_A_1_B_1 8i5c_A_1_B_1 8i5c_EA_1_FA_1 8i5c_F_1_G_1 8i5c_JA_1_KA_1 8i5c_K_1_L_1 8i5c_OA_1_PA_1 8i5c_P_1_Q_1 8i5c_TA_1_UA_1 8i5c_U_1_V_1 8i5c_Z_1_AA_1 8i5d_C_1_D_1 8i5e_A_1_B_1 8rbu_A_1_B_1 8rh6_A_1_B_1 8rh6_C_1_D_1 8rh6_E_1_F_1 8rhq_A_1_B_1 8rhq_C_1_D_1 8rhq_E_1_F_1 8wte_C_1_D_1 8wte_H_1_I_1 8wul_I_1_J_1 8wul_L_1_M_1 8wul_O_1_P_1 8wul_R_1_S_1 [2108:POL_HV1Z2 ] 1q94_A_1_C_1 1q94_D_1_F_1 6id4_A_1_J_1 6id4_E_1_I_1 [2739:NEF_HV1Z6 ] 1qvo_A_1_C_1 1qvo_D_1_F_1 [1605:NCAP_CVHSA ] 1x7q_A_1_C_1 7wkj_A_1_C_1 [2534 ] 2hn7_A_1_C_1 [1725:MYPR_HUMAN ] 2xpg_A_1_C_1 [3449:R4P6M5_9INFA ] 4mj5_A_1_C_1 [3131:R4X2K3_9INFA ] 4mj6_A_1_C_1 [2133:A14_VACCW ] 4n8v_C_1_E_1 4n8v_F_1_H_1 [3524 ] 4uq2_A_1_F_1 4uq2_C_1_E_1 [2411 ] 5grd_A_1_C_1 [706 ] 5grg_A_1_C_1 [862 ] 5gsd_A_1_C_1 [2737 ] 5wjl_A_1_C_1 5wjl_D_1_F_1 5wjl_G_1_I_1 5wkf_A_1_C_1 5wkf_F_1_H_1 [2738 ] 5wjn_A_1_C_1 5wjn_D_1_F_1 5wjn_G_1_I_1 5wkh_A_1_C_1 5wkh_F_1_H_1 [1893 ] 6j29_A_1_B_1 [1814 ] 6joz_A_1_C_1 [469 ] 6jp3_A_1_C_1 [2045:PK3CA_HUMAN ] 7l1c_A_1_C_1 7l1d_A_2_C_2 7rrg_A_1_E_1 [1777:SPIKE_SARS2 ] 7m8t_A_1_C_1 [2966:RASN_HUMAN ] 7ow3_A_1_C_1 7ow3_J_1_L_1 7ow5_A_1_C_1 [2939:RASN_HUMAN ] 7ow3_D_1_F_1 [2875:RASN_HUMAN ] 7ow3_G_1_I_1 [2965:RASN_HUMAN ] 7ow4_A_1_C_1 7ow4_D_1_F_1 7ow4_G_1_I_1 7ow4_J_1_L_1 [2961:RASN_HUMAN ] 7ow6_A_1_C_1 7pb2_A_1_C_1 7pb2_F_1_H_1 [2933:NCAP_INBSI ] 7s8q_A_1_C_1 7s8q_D_1_F_1 [2165:M1_INBAC ] 7s8r_A_1_C_1 7s8r_D_1_F_1 [2971:NS1_INBSJ ] 7s8s_A_1_C_1 [1943:NCAP_I46A1 ] 7uc5_A_1_C_1 7uc5_D_1_F_1 [2059 ] 8i5c_A_1_C_1 8i5c_EA_1_GA_1 8i5c_F_1_H_1 8i5c_JA_1_LA_1 8i5c_K_1_M_1 8i5c_OA_1_QA_1 8i5c_P_1_R_1 8i5c_TA_1_VA_1 8i5c_U_1_W_1 8i5c_Z_1_BA_1 8i5d_C_1_E_1 8wte_C_1_E_1 8wte_H_1_J_1 8wul_I_1_K_1 8wul_L_1_N_1 8wul_O_1_Q_1 8wul_R_1_T_1 [1650:RASK_HUMAN ] 8i5e_A_1_C_1 [3031:SPIKE_SARS2 ] 8rbu_A_1_C_1 [2774:SPIKE_SARS2 ] 8rh6_A_1_I_1 8rh6_C_1_H_1 8rh6_E_1_G_1 [3030:SPIKE_SARS2 ] 8rhq_A_1_G_1 8rhq_C_1_H_1 8rhq_E_1_I_1


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