Summary for the 101-st Site(D)
PID QueryLength FocusSite TITLE
2931865 365 101 D RecName: Full=HLA class I histocompatibility antigen, A alpha chain;AltName: Full=Human leukocyte antigen A; Short=HLA-A;Flags: Precursor;
UniProt Information
AC/IDAC:P04439 ID:HLAA_HUMAN
Feature Table for 101-th site VARIANT: /note="D -> N (allele A*01:01, allele A*23:01, allele A*24:02, allele A*26:01, allele A*29:02, allele A*36:01, allele A*43:01 and allele A*80:01; dbSNP:rs1136688)" ECO:0000269|PubMed:1729171, ECO:0000269|PubMed:1782566, ECO:0000269|PubMed:2251137, ECO:0000269|PubMed:2715640, ECO:0000269|PubMed:8026990, ECO:0000269|PubMed:8188325, ECO:0000269|PubMed:8284791, ECO:0000269|PubMed:8475492, ECO:0000269|PubMed:9349616, ECO:0000269|PubMed:9349617" /id="VAR_082345"
VARIANT: /note="D -> S (in allele A*25:01 and allele A*32:01; requires 2 nucleotide substitutions)" ECO:0000269|PubMed:2431040, ECO:0000269|Ref.29" /id="VAR_082346"
HELIX:
REGION: /note="Alpha-1"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="HLA class I histocompatibility antigen, A alpha chain" /id="PRO_0000018815"
VARIANT for 101-th site D->N LB/B dbSNP:rs1136688 " -"
D->S LB/B " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
D:30% E:17% N:13% T:8% F:7% S:7% A:4% G:4% M:4% V:3%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
6o9c H (alpha-helix) e (exposed) 32.7
3D Complex Information
Predicted Bind Molecules
hetero:90
Templates for 3D complexes
hetero [2108:POL_HV1Z2 ] 1q94_A_1_C_1 1q94_D_1_F_1 3rl1_A_1_C_1 6id4_A_1_J_1 6id4_E_1_I_1 6j1v_A_1_C_1 6j1w_A_1_B_1 8erx_A_1_C_1 [2739:NEF_HV1Z6 ] 1qvo_A_1_C_1 1qvo_D_1_F_1 3rl2_A_1_C_1 [1605:NCAP_CVHSA ] 1x7q_A_1_C_1 7wkj_A_1_C_1 [2534 ] 2hn7_A_1_C_1 [1725:MYPR_HUMAN ] 2xpg_A_1_C_1 [3449:R4P6M5_9INFA ] 4mj5_A_1_C_1 [3131:R4X2K3_9INFA ] 4mj6_A_1_C_1 [2133:A14_VACCW ] 4n8v_C_1_E_1 4n8v_F_1_H_1 [2411 ] 5grd_A_1_C_1 [192 ] 5grg_A_1_D_1 [862 ] 5gsd_A_1_C_1 [2737 ] 5wjl_A_1_C_1 5wjl_D_1_F_1 5wjl_G_1_I_1 5wkf_A_1_C_1 5wkf_F_1_H_1 [2738 ] 5wjn_A_1_C_1 5wjn_D_1_F_1 5wjn_G_1_I_1 5wkh_A_1_C_1 5wkh_F_1_H_1 [1893 ] 6j29_A_1_B_1 [2061 ] 6j2a_A_1_C_1 [1814 ] 6joz_A_1_C_1 [195 ] 6jp3_A_1_D_1 [1600:CTNB1_HUMAN ] 6o9b_A_1_C_1 [1610:CTNB1_HUMAN ] 6o9c_A_1_C_1 [1747:PK3CA_HUMAN ] 7l1b_A_1_C_1 [2045:PK3CA_HUMAN ] 7l1c_A_1_C_1 7l1d_A_2_C_2 7rrg_A_1_E_1 [1777:SPIKE_SARS2 ] 7m8t_A_1_C_1 [1938:NCAP_INBAC ] 7mle_A_1_C_1 [2966:RASN_HUMAN ] 7ow3_A_1_C_1 7ow3_J_1_L_1 7ow5_A_1_C_1 8dvg_A_1_C_1 [2939:RASN_HUMAN ] 7ow3_D_1_F_1 [2875:RASN_HUMAN ] 7ow3_G_1_I_1 [2965:RASN_HUMAN ] 7ow4_A_1_C_1 7ow4_D_1_F_1 7ow4_G_1_I_1 7ow4_J_1_L_1 [2961:RASN_HUMAN ] 7ow6_A_1_C_1 7pb2_A_1_C_1 7pb2_F_1_H_1 [2933:NCAP_INBSI ] 7s8q_A_1_C_1 7s8q_D_1_F_1 [2165:M1_INBAC ] 7s8r_A_1_C_1 7s8r_D_1_F_1 [2971:NS1_INBSJ ] 7s8s_A_1_C_1 [2536 ] 7stf_D_1_B_1 [1943:NCAP_I46A1 ] 7uc5_A_1_C_1 7uc5_D_1_F_1 [2059 ] 8i5c_A_1_C_1 8i5c_EA_1_GA_1 8i5c_F_1_H_1 8i5c_JA_1_LA_1 8i5c_K_1_M_1 8i5c_OA_1_QA_1 8i5c_P_1_R_1 8i5c_TA_1_VA_1 8i5c_U_1_W_1 8i5c_Z_1_BA_1 8i5d_C_1_E_1 8wte_C_1_E_1 8wte_H_1_J_1 8wul_I_1_K_1 8wul_L_1_N_1 8wul_O_1_Q_1 8wul_R_1_T_1 [1650:RASK_HUMAN ] 8i5e_A_1_C_1 [3031:SPIKE_SARS2 ] 8rbu_A_1_C_1 [2774:SPIKE_SARS2 ] 8rh6_A_1_I_1 8rh6_C_1_H_1 8rh6_E_1_G_1 [3030:SPIKE_SARS2 ] 8rhq_A_1_G_1 8rhq_C_1_H_1 8rhq_E_1_I_1


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