Summary for the 86-th Site(Q)
PID QueryLength FocusSite TITLE
2931865 365 86 Q RecName: Full=HLA class I histocompatibility antigen, A alpha chain;AltName: Full=Human leukocyte antigen A; Short=HLA-A;Flags: Precursor;
UniProt Information
AC/IDAC:P04439 ID:HLAA_HUMAN
Feature Table for 86-th site VARIANT: /note="Q -> E (in allele A*23:01, allele 24:02 and allele A*80:01)" ECO:0000269|PubMed:8188325, ECO:0000269|PubMed:8284791, ECO:0000269|PubMed:9349616" /id="VAR_082330"
VARIANT: /note="Q -> G (in allele A*02:01 and allele A*02:05; requires 2 nucleotide substitutions)" ECO:0000269|PubMed:2982951, ECO:0000269|PubMed:3496393, ECO:0000269|PubMed:7836067" /id="VAR_082331"
VARIANT: /note="Q -> L (in alleles A*29:02 and allele A*43:01)" ECO:0000269|PubMed:1782566" /id="VAR_082332"
VARIANT: /note="Q -> R (in allele A*25:01, allele A*26:01, allele A*33:01, allele A*34:01, allele A*66:01, allele A*68:01 and allele A*69:01)" ECO:0000269|PubMed:2320591, ECO:0000269|PubMed:2478623, ECO:0000269|PubMed:3877632, ECO:0000269|PubMed:8026990, ECO:0000269|PubMed:8475492" /id="VAR_082333"
HELIX:
REGION: /note="Alpha-1"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="HLA class I histocompatibility antigen, A alpha chain" /id="PRO_0000018815"
VARIANT for 86-th site Q->E LB/B " -"
Q->G LB/B " -"
Q->L LB/B " -"
Q->R LB/B " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
R:35% K:20% Q:13% N:9% G:8% E:7% T:3% H:1% L:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
6o9c H (alpha-helix) e (exposed) 54.1
3D Complex Information
Predicted Bind Molecules
hetero:173 compound:1 precipitant:24
Templates for 3D complexes
hetero [49795 ] 1bd2_A_1_D_1 [2739:NEF_HV1Z6 ] 1qvo_A_1_C_1 1qvo_D_1_F_1 3rl2_A_1_C_1 [2066:MAG1_HUMAN ] 1w72_A_1_C_1 [1605:NCAP_CVHSA ] 1x7q_A_1_C_1 7wkj_A_1_C_1 [47513:Q6PIZ8_HUMAN ] 2f53_A_1_D_1 2p5w_A_1_D_1 [47918 ] 2j8u_A_1_D_1 2j8u_F_1_I_1 [1725:MYPR_HUMAN ] 2xpg_A_1_C_1 [54497 ] 3gjf_A_1_I_1 3gjf_D_1_J_1 [48863 ] 3gsn_A_1_D_1 [46903 ] 3hg1_A_1_D_1 3qdg_A_1_D_1 3qdj_A_1_D_1 3vxu_A_1_D_1 3vxu_F_1_I_1 3w0w_A_1_D_1 4l3e_A_1_D_1 4qok_A_1_D_1 6am5_A_1_D_1 6dkp_A_1_D_1 6eqa_A_1_D_1 7pbc_A_1_C_1 7pdw_I_1_A_1 7pdw_J_1_E_1 7q99_A_1_D_1 7q9a_A_1_D_1 7qpj_A_1_D_1 8dnt_D_1_A_1 8dnt_I_1_F_1 8dnt_N_1_K_1 [48012 ] 3o4l_A_1_D_1 [47839 ] 3qeq_A_1_D_1 [2108:Q9YV12_9HIV1 ] 3rl1_A_1_C_1 4hwz_A_1_C_1 6id4_E_1_I_1 8erx_A_1_C_1 [47323 ] 3uts_A_1_D_1 3uts_F_1_I_1 3utt_A_1_D_1 3utt_F_1_I_1 5c08_A_1_D_1 5c08_F_1_I_1 5c0b_F_1_I_1 5c0c_A_1_I_1 5c0c_F_1_D_1 5hyj_A_1_D_1 5hyj_F_1_I_1 [51313 ] 3vxm_A_1_D_1 [3004:Q9YYU8_9HIV1 ] 3vxn_A_1_C_1 3vxr_A_1_E_1 [2889:Q9YYU3_9HIV1 ] 3vxo_A_1_E_1 3vxo_C_1_F_1 3vxu_F_1_H_1 3w0w_A_1_C_1 5hgd_A_1_C_1 5hgd_D_1_F_1 [2565:Q9WPU2_9HIV1 ] 3vxp_A_1_C_1 3vxp_D_1_F_1 [49980 ] 3vxr_A_1_C_1 3vxs_A_1_C_1 [1876:O75767_HUMAN ] 4hx1_A_1_C_1 [1682:ENV_HV1LW ] 4i48_A_1_C_1 [48167 ] 4jfd_A_1_D_1 4jfe_A_1_D_1 4jff_A_1_D_1 6eqb_A_1_D_1 6tmo_A_1_D_1 [3449:R4P6M5_9INFA ] 4mj5_A_1_C_1 [3131:R4X2K3_9INFA ] 4mj6_A_1_C_1 [2133:A14_VACCW ] 4n8v_C_1_E_1 4n8v_F_1_H_1 [2061 ] 4nqv_A_1_M_1 4nqv_C_1_N_1 4nqv_E_1_O_1 4nqv_I_1_Q_1 4nqv_K_1_R_1 6j2a_A_1_C_1 [2060 ] 4nqx_A_1_M_1 4nqx_C_1_N_1 4nqx_E_1_O_1 4nqx_I_1_Q_1 4nqx_K_1_R_1 [51660 ] 4wuu_A_1_D_1 [55665 ] 4wuu_A_1_E_1 [1867 ] 5brz_A_1_C_1 [48458:A0A0B4J279_HUMAN :TCA_HUMAN ] 5brz_A_1_D_1 5bs0_A_1_D_1 [1714:TITIN_HUMAN ] 5bs0_A_1_C_1 [27619:A0A075B6T6_HUMAN ] 5e9d_F_1_I_1 [49783 ] 5eu6_A_1_D_1 [2411 ] 5grd_A_1_C_1 [49034 ] 5nme_A_1_D_1 5nme_F_1_I_1 5nmf_A_1_D_1 5nmf_F_1_I_1 5nmg_A_1_D_1 5nmg_F_1_I_1 [48569:A0A087WSZ9_HUMAN :K7N5N2_HUMAN ] 5wkf_A_1_D_1 5wkf_F_1_I_1 5wkh_A_1_D_1 5wkh_F_1_I_1 [3296 ] 5wxc_C_1_F_1 [50468 ] 5xov_A_1_G_1 5xov_D_1_I_1 [47311 ] 5yxn_C_1_A_1 [48939:K7N5M3_HUMAN ] 6d78_A_1_D_1 [2842:CCND2_HUMAN ] 6ei2_A_1_C_1 [1893 ] 6j29_A_1_B_1 [469 ] 6jp3_A_1_C_1 [50545 ] 6p64_A_1_E_3 [3695 ] 6pbh_A_1_C_1 [47915:TVA22_HUMAN :K7N5M3_HUMAN ] 6r2l_A_1_D_1 [51631 ] 6rpa_A_1_D_1 [50713 ] 6rsy_A_1_D_1 6rsy_F_1_I_1 [50673 ] 6tro_A_1_D_1 [50571 ] 6vm7_C_1_A_2 [50191 ] 6vm9_A_1_D_2 6vma_A_1_C_2 6vmc_C_1_A_2 [50043 ] 6w51_G_1_R_2 [55661 ] 7bbg_A_1_D_1 [1861 ] 7ejn_A_1_C_1 [1434 ] 7k80_A_1_C_1 7k80_D_1_F_1 7k81_A_2_C_2 8gvb_C_1_E_1 8gvi_C_1_E_1 [49570 ] 7ow5_A_1_D_1 [49599 ] 7ow6_A_1_D_1 [49596 ] 7pb2_A_1_D_1 7pb2_F_1_I_1 [55880 ] 7re7_E_1_C_1 7re7_G_1_A_2 [50433 ] 7rrg_A_1_C_2 [2045:PK3CA_HUMAN ] 7rrg_A_1_E_1 [2971:NS1_INBSJ ] 7s8s_A_1_C_1 [2028:SPIKE_SARS2 ] 7tlt_A_1_E_1 7tlt_C_1_F_1 [1943:NCAP_I46A1 ] 7uc5_A_1_C_1 7uc5_D_1_F_1 [1370:RDRP_I97A1 ] 7wt4_A_1_C_1 [1332 ] 7wt5_A_1_C_1 7wt5_D_1_F_1 [88307 ] 8ek5_A_1_D_1 [67109 ] 8es8_I_1_G_1 [2030 ] 8esh_A_1_C_1 [50470 ] 8gom_A_1_D_1 [50873 ] 8gvb_C_1_A_1 [60272 ] 8gvb_C_1_B_1 [50110 ] 8gvg_C_1_A_1 8gvi_C_1_A_1 [1330 ] 8gvg_C_1_E_1 [48734 ] 8i5c_A_1_D_1 8i5c_EA_1_HA_1 8i5c_F_1_I_1 8i5c_JA_1_MA_1 8i5c_K_1_N_1 8i5c_OA_1_RA_1 8i5c_P_1_S_1 8i5c_TA_1_WA_1 8i5c_U_1_X_1 8i5c_Z_1_CA_1 [47796 ] 8i5d_C_1_A_1 [48503 ] 8wte_H_1_F_1 8wul_L_1_C_1 [59962 ] 8wte_H_1_G_1 8wul_L_1_D_1 compound [PE8 ] 6z9v_D_1_Z_1 precipitant [GOL ] 1tvb_D_1_S_1 1tvh_A_1_J_1 1tvh_D_1_X_1 2gtz_A_1_I_1 2p5e_A_1_F_1 3fqt_A_1_M_1 3fqu_A_1_D_1 3o3a_D_1_M_1 3o3e_D_1_J_1 5eu6_A_1_L_1 6pte_A_1_M_1 6pte_D_1_Q_1 6pte_G_1_U_1 6pte_J_1_Z_1 6tmo_A_1_F_1 7lg2_A_1_D_1 7qpj_A_1_H_1 7tr4_A_1_F_1 [SO4 ] 1x7q_A_1_E_1 2hn7_A_1_F_1 [EDO ] 5nmg_A_1_K_1 6tdr_C_1_K_1 6trn_A_1_D_1 6z9v_A_1_H_1


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