Summary for the 218-th Site(I)
PID QueryLength FocusSite TITLE
2931865 365 218 I RecName: Full=HLA class I histocompatibility antigen, A alpha chain;AltName: Full=Human leukocyte antigen A; Short=HLA-A;Flags: Precursor;
UniProt Information
AC/IDAC:P04439 ID:HLAA_HUMAN
Feature Table for 218-th site VARIANT: /note="I -> V (in allele A*02:01, allele A*02:05, allele A*25:01, allele A*26:01, allele A*29:02, allele A*31:01, allele A*32:01, allele A*33:01, allele A*34:01, allele A*43:01, allele A*66:01, allele A*68:01, allele A*69:01 and allele A*74:01)" ECO:0000269|PubMed:1431115, ECO:0000269|PubMed:1782566, ECO:0000269|PubMed:2320591, ECO:0000269|PubMed:2431040, ECO:0000269|PubMed:2478623, ECO:0000269|PubMed:2982951, ECO:0000269|PubMed:3496393, ECO:0000269|PubMed:3877632, ECO:0000269|PubMed:7836067, ECO:0000269|PubMed:8026990, ECO:0000269|PubMed:8475492, ECO:0000269|PubMed:8795145, ECO:0000269|Ref.29" /id="VAR_082386"
STRAND:
DOMAIN: /note="Ig-like C1-type"
REGION: /note="Alpha-3"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="HLA class I histocompatibility antigen, A alpha chain" /id="PRO_0000018815"
VARIANT for 218-th site I->V LB/B " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
V:18% A:17% L:12% S:9% T:9% I:8% Y:7% R:5% G:5% E:4% P:3% F:2% N:1% D:1% Q:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
6o9c S (bend) e (exposed) 55.0
3D Complex Information
Predicted Bind Molecules
hetero:16 precipitant:4
Templates for 3D complexes
hetero [48031:LIRB1_HUMAN ] 1p7q_A_1_D_1 4no0_A_1_D_1 6ewa_E_1_H_1 6ewc_A_1_D_1 6ewc_E_1_H_1 6ewo_A_1_D_1 6ewo_E_1_H_1 [48170:LIRB2_HUMAN ] 2dyp_A_1_D_1 [65288:LIRB1_HUMAN ] 5knm_A_1_C_1 [82911:A0A0G2JQ44_HUMAN ] 6aee_A_1_G_1 6aee_D_1_H_1 [48102:D9IDM8_HUMAN ] 6ewa_A_1_D_1 [48634:A0A0G2JQ44_HUMAN ] 6k60_E_1_H_1 [55704 ] 6w51_A_1_M_1 6w51_J_1_S_1 [83115:TPSN_HUMAN ] 7tue_A_1_B_1 precipitant [GOL ] 1w0v_A_1_E_1 3b3i_A_1_F_1 [PEG ] 3rwe_A_1_D_1 [EDO ] 6o9b_A_1_K_1


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