Summary for the 158-th Site(T)
PID QueryLength FocusSite TITLE
2931865 365 158 T RecName: Full=HLA class I histocompatibility antigen, A alpha chain;AltName: Full=Human leukocyte antigen A; Short=HLA-A;Flags: Precursor;
UniProt Information
AC/IDAC:P04439 ID:HLAA_HUMAN
Feature Table for 158-th site MUTAGEN: /note="T->K: Impairs binding to TAP1-TAP2 transporter, resulting in impaired presentation of intracellular peptides." ECO:0000269|PubMed:8805302"
STRAND:
REGION: /note="Alpha-2"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="HLA class I histocompatibility antigen, A alpha chain" /id="PRO_0000018815"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
T:33% R:18% E:9% V:8% P:6% S:6% Q:4% L:4% A:2% D:2% G:2% I:2% K:2% H:1% M:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
6o9c E (beta-strand) e (exposed) 48.7
3D Complex Information
Predicted Bind Molecules
hetero:6 homo:2 metal:7 precipitant:45
Templates for 3D complexes
hetero [50234 ] 4qrp_F_1_K_1 [30420:KLRA3_MOUSE ] 5j6g_A_1_G_1 5j6g_C_1_H_1 [85471:TPSN_HUMAN ] 7qpd_D_1_B_1 [60146 ] 7su9_C_1_B_1 [83115:TPSN_HUMAN ] 7tue_A_1_B_1 homo [65828:1A02_HUMAN ] 3bh9_A_1_A_2 3bh9_A_2_A_1 metal [NA ] 3bh9_A_1_D_1 3bh9_A_2_D_2 3sko_A_1_D_1 7jyw_A_1_F_1 [CL ] 4l3c_M_1_HB_1 7lgt_A_1_Q_1 [MG ] 7jyv_A_1_E_1 precipitant [GOL ] 2av7_A_1_M_1 3dx8_A_1_D_1 3pwp_A_1_I_1 4ftv_A_1_I_1 5c0c_F_1_IA_1 5eu5_A_1_U_1 5npz_A_1_E_1 [SO4 ] 2gj6_A_1_F_1 4gkn_A_1_I_1 4jfp_A_1_J_1 5c07_F_1_U_1 6r2l_A_1_K_1 [EDO ] 4u1h_A_1_D_1 4u1i_A_1_F_1 4u1k_A_1_K_1 4u1k_D_1_U_1 4u1l_A_1_M_1 4u1l_D_1_W_1 4u1m_A_1_D_1 4u1n_A_1_G_1 4u1s_A_1_F_1 4zfz_G_1_KB_1 4zfz_J_1_FC_1 5c08_F_1_FA_1 5c0c_F_1_CA_1 5eu6_A_1_F_1 5mer_D_1_Y_1 5nme_A_1_L_1 5nmf_F_1_EA_1 5nmk_A_1_H_1 5nq0_A_1_I_1 6iwg_A_1_I_1 6iwh_A_1_I_1 6lah_A_1_I_1 6lam_A_1_H_1 6lb2_C_1_KA_1 7wj2_A_1_D_1 7wj3_A_1_D_1 7wj3_A_1_H_1 8roo_A_1_D_1 8sbk_A_1_E_1 8tub_B_1_O_1 [PG4 ] 5c0c_A_1_N_1 [PEG ] 6uj9_A_1_F_1 [PGE ] 7s8a_A_1_G_1


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