Summary for the 277-th Site(E)

PID QueryLength FocusSite TITLE
2931865 365 277 E RecName: Full=HLA class I histocompatibility antigen, A alpha chain;AltName: Full=Human leukocyte antigen A; Short=HLA-A;Flags: Precursor;
UniProt Information
AC/IDAC:P04439 ID:HLAA_HUMAN
Feature Table for 277-th site VARIANT: /note="E -> K (in allele A*80:01)" ECO:0000269|PubMed:8284791" /id="VAR_082390"
VARIANT: /note="E -> Q (in allele A*02:01, allele A*02:05, allele A*25:01, allele A*26:01, allele A*29:02, allele A*31:01, allele A*32:01, allele A*33:01, allele A*34:01, allele A*43:01, allele A*66:01, allele A*68:01, allele A*69:01 and allele A*74:01)" ECO:0000269|PubMed:1431115, ECO:0000269|PubMed:1782566, ECO:0000269|PubMed:2320591, ECO:0000269|PubMed:2431040, ECO:0000269|PubMed:2478623, ECO:0000269|PubMed:2982951, ECO:0000269|PubMed:3496393, ECO:0000269|PubMed:3877632, ECO:0000269|PubMed:7836067, ECO:0000269|PubMed:8026990, ECO:0000269|PubMed:8475492, ECO:0000269|PubMed:8795145, ECO:0000269|Ref.29" /id="VAR_082391"
STRAND:
DOMAIN: /note="Ig-like C1-type"
REGION: /note="Alpha-3"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="HLA class I histocompatibility antigen, A alpha chain" /id="PRO_0000018815"
VARIANT for 277-th site E->K LB/B " -"
E->Q LB/B " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
E:30% D:16% S:12% Q:9% N:6% R:5% K:4% P:4% A:3% T:3% V:3% L:2% Y:2% G:1% H:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8dvg (coil) e (exposed) 33.2


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