Summary for the 140-th Site(D)
PID QueryLength FocusSite TITLE
2931865 365 140 D RecName: Full=HLA class I histocompatibility antigen, A alpha chain;AltName: Full=Human leukocyte antigen A; Short=HLA-A;Flags: Precursor;
UniProt Information
AC/IDAC:P04439 ID:HLAA_HUMAN
Feature Table for 140-th site BINDING: /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen"
VARIANT: /note="D -> H (in allele A*30:01)" ECO:0000269|PubMed:7871528" /id="VAR_082360"
VARIANT: /note="D -> Y (in allele A*02:01, allele A*02:05, allele A*23:01, allele A*24:02 and allele A*69:01)" ECO:0000269|PubMed:2320591, ECO:0000269|PubMed:2982951, ECO:0000269|PubMed:3496393, ECO:0000269|PubMed:3877632, ECO:0000269|PubMed:7836067, ECO:0000269|PubMed:9349616" /id="VAR_082361"
STRAND:
REGION: /note="Alpha-2"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="HLA class I histocompatibility antigen, A alpha chain" /id="PRO_0000018815"
VARIANT for 140-th site D->H LB/B " -"
D->Y LB/B " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
Y:22% F:21% V:11% L:8% G:7% E:6% A:5% H:5% D:4% M:3% I:2% S:2% R:1% N:1% K:1% P:1% T:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8dvg E (beta-strand) b (buried) 10.5
3D Complex Information
Predicted Bind Molecules
hetero:22
Templates for 3D complexes
hetero [22561:B2MG_HUMAN ] 2xpg_A_1_B_1 3rl1_A_1_B_1 3rl2_A_1_B_1 7l1b_A_1_B_1 7l1c_A_1_B_1 7mle_A_1_B_1 7rrg_A_1_B_1 7uc5_A_1_B_1 7uc5_D_1_E_1 8dvg_A_1_B_1 [1725:MYPR_HUMAN ] 2xpg_A_1_C_1 [2108:Q9YV12_9HIV1 ] 3rl1_A_1_C_1 [2739:Q9YYU8_9HIV1 ] 3rl2_A_1_C_1 [1747:PK3CA_HUMAN ] 7l1b_A_1_C_1 [2045:PK3CA_HUMAN ] 7l1c_A_1_C_1 7l1d_A_2_C_2 7rrg_A_1_E_1 [1938:NCAP_INBAC ] 7mle_A_1_C_1 [2536 ] 7stf_D_1_B_1 [1943:NCAP_I46A1 ] 7uc5_A_1_C_1 7uc5_D_1_F_1 [2966 ] 8dvg_A_1_C_1


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