Summary for the 10-th Site(L)

PID QueryLength FocusSite TITLE
2931865 365 10 L RecName: Full=HLA class I histocompatibility antigen, A alpha chain;AltName: Full=Human leukocyte antigen A; Short=HLA-A;Flags: Precursor;
UniProt Information
AC/IDAC:P04439 ID:HLAA_HUMAN
Feature Table for 10-th site VARIANT: /note="L -> V (in allele A*02:01, allele A*02:05, allele A*23:01, allele A*24:02, allele A*25:01, allele A*26:01, allele A*34:01, allele A*43:01, allele A*66:01, allele A*68:01 and allele A*69:01; does not alter the affinity of VL9 peptide for HLA-E or HLA-E expression at the plasma membrane; decreases KLRD1-KLRC1 and KLRD1-KLRC2 receptor engagement and signaling)" ECO:0000269|PubMed:1729171, ECO:0000269|PubMed:2320591, ECO:0000269|PubMed:2982951, ECO:0000269|PubMed:3496393, ECO:0000269|PubMed:37264229, ECO:0000269|PubMed:3877632, ECO:0000269|PubMed:7836067, ECO:0000269|PubMed:8026990, ECO:0000269|PubMed:8475492, ECO:0000269|PubMed:9349616" /id="VAR_082317"
REGION: /note="VL9 epitope"
SIGNAL:
VARIANT for 10-th site L->V LB/B " -"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
L:70% F:21% V:7% I:3% 


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